心脏瓣膜钙化对老年冠心病病人预后的影响

doi:10.3969/j.issn.1003-9198.2024.03.008

Abstract

Abstract: Objective To investigate the correlation between cardiac valve calcification(CVC) and major adverse cardiac and cerebral events(MACCE) in the elderly patients with coronary heart disease(CHD). Methods A total of 140 elderly patients with CHD were enrolled. The patients were divided into CVC group and non-CVC group according to echocardiography. The patients were followed up, and the incidence rate of MACCE and all-cause death were recorded and compared between the two groups by Kaplan-Meier method, and the influencing factors of MACCE were analyzed by Multivariate Cox proportional hazards models. Results There were significant differences in age, total cholesterol(TC), low-density lipoprotein cholesterol(LDL-C), albumin, and estimated glomerular filtration rate(eGFR) between the two groups(P<0.05 or P<0. 01). After 5 years of follow-up, the incidence rate of MACCE and all-cause mortality in the CVC group were higher than those in the non-CVC group(P<0.001, P=0.002). Cox regression analysis showed that CVC, urea nitrogen and left atrial diameter increased the risk of MACCE, but CVC did not increase the risk of all-cause death. Conclusions Old age and poor renal function are more prone to presenting with CVC in the elderly patients with CHD. CVC is an independent risk factor for MACCE, and the prognosis is worse in the patients with CVC.

Key words: aged, coronary heart disease, cardiac valve calcification, major adverse cardiac and cerebral event

CLC Number:

R 541.4

ZHA Zhimin, LIU Huan, WANG Xiangming, LI Qiushuang, GUO Yan. Effect of cardiac valve calcification on prognosis of elderly patients with coronary heart disease[J]. Practical Geriatrics, 2024, 38(3): 245-250.

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Effect of cardiac valve calcification on prognosis of elderly patients with coronary heart disease

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