老年肺腺癌病人术前全身免疫炎症指数/血清白蛋白与临床病理特征的相关性研究

doi:10.3969/j.issn.1003-9198.2024.09.008

Abstract

Abstract: Objective To investigate the correlation between preoperative systemic immunoinflammatory index/serum albumin (SII/ALB) and clinicopathological features in the elderly patients with lung adenocarcinoma. Methods The clinicopathological data of 103 elderly patients with lung adenocarcinoma treated by thoracoscopic surgery in Geriatric Hospital of Nanjing Medical University from January 2020 to June 2023 were retrospectively analyzed. SII/ALB value was calculated according to preoperative test results, and the patients were divided into high SII/ALB group and low SII/ALB group according to the median SII/ALB value. The relationship between SII/ALB and clinicopathological features of the patients was analyzed. Results The median SII/ALB was 16.1, and there were 47 cases in low SII/ALB group (SII/ALB≤16.1) and 56 cases in high SII/ALB group (SII/ALB > 16.1). There were significant differences in BMI, high-grade adenocarcinoma components, pleural invasion, TNM stage, lymph node metastasis and airway spread between the two groups (P<0.05). The level ofSII/ALB was correlated with TNM stage and lymph node metastasis (P<0.05). Conclusions SII/ALB reflects the immune, inflammatory and nutritional status of the patients. SII/ALB level is related to TNM stage and lymph node metastasis. Monitoring SII/ALB level is helpful to provide certain reference information for the clinical diagnosis and treatment of elderly lung adenocarcinoma.

Key words: lung tumor, adenocarcinoma, systemic immunoinflammatory index/serum albumin, clinicopathological features, correlation, aged

CLC Number:

R734.2

LI Jiang, QIU Yan, WANG Ting, WANG Dan, YU Yifan, PU Lingli, BU Ling. Correlation between preoperative SII/ALB and clinicopathologic features in elderly patients with lung adenocarcinoma[J]. Practical Geriatrics, 2024, 38(9): 893-896.

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Correlation between preoperative SII/ALB and clinicopathologic features in elderly patients with lung adenocarcinoma

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