老年人炎症与肌少症相关性的研究进展

doi:10.3969/j.issn.1003-9198.2025.07.002

摘要/Abstract

摘要： 肌少症是一种与年龄增长相关的肌肉质量、力量及功能下降的老年综合征,严重影响老年人的生活质量并且增加了多种不良健康结局的风险。激素水平的改变、线粒体功能减退、神经肌肉接头退化、营养摄入不足、缺乏运动、慢性疾病等均与肌少症的发生有关,而炎症状态在肌少症的发生发展过程中起着关键作用。本文简要综述了炎症与肌少症之间的研究进展,旨在深入理解炎症与肌少症之间的相互作用关系,为开发有效的肌少症防治措施提供参考。

关键词: 肌少症, 炎症, 共病, 老年人

Abstract: Sarcopenia is a geriatric syndrome characterized by the decline in muscle mass, strength, and function associated with aging. It severely affects the quality of life of the elderly and increases the risk of various adverse health outcomes. Changes in hormone levels, mitochondrial dysfunction, degeneration of neuromuscular junctions, insufficient nutritional intake, lack of physical activity, chronic diseases, etc. are all related to the occurrence of sarcopenia. Among them, inflammation plays a crucial role in the occurrence and development of sarcopenia. This article reviews the research progress on the relationship between inflammation and sarcopenia, aiming to deeply understand the interaction between inflammation and sarcopenia, and provide a reference for the development of effective prevention and treatment measures.

Key words: sarcopenia, inflammation, comorbidity, aged

中图分类号:

R685

易鑫枚, 张飞, 王佳贺. 老年人炎症与肌少症相关性的研究进展[J]. 实用老年医学, 2025, 39(7): 654-658.

YI Xinmei, ZHANG Fei, WANG Jiahe. Research progress on the association between inflammation and sarcopenia in the elderly[J]. Practical Geriatrics, 2025, 39(7): 654-658.

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