炎症与睡眠障碍的研究进展

doi:10.3969/j.issn.1003-9198.2025.06.002

摘要/Abstract

摘要： 睡眠障碍在全球范围内广泛影响成年人,尤其在老年人群中更为突出,其与炎症之间存在复杂的双向关系,对人体健康影响深远。本文深入探讨了睡眠障碍与炎症的相互作用机制,分述了睡眠障碍对炎症因子的影响,如激活炎症信号通路导致炎性因子增加;以及炎症对睡眠的影响,如干扰睡眠结构和模式等,创新性地提出通过药物和行为干预调节睡眠-免疫能力,打破二者的恶性循环,进而改善睡眠障碍、减缓疾病进展。未来研究应聚焦于睡眠障碍与炎症相互作用的分子机制,为开发更精准有效的干预措施提供理论依据。临床治疗中,建议将睡眠障碍和炎症的治疗纳入综合治疗方案,以提高病人生活质量,降低疾病风险。

关键词: 睡眠障碍, 炎症, 相关性研究

Abstract: Sleep disorders widely affect adults globally, being particularly prominent among the elderly. There is a complex bidirectional relationship between sleep disorders and inflammation, which has a profound impact on human health. This article delves into the interaction mechanisms between sleep disorders and inflammation. It separately describes the effects of sleep disorders on inflammatory factors, such as activating inflammatory signaling pathways and leading to an increase in inflammatory factors, as well as the impact of inflammation on sleep, like interfering with sleep structure and patterns. Innovatively, it is proposed to regulate sleep-immune function through drug and behavioral interventions to break the vicious cycle between sleep disorders and inflammation, thereby improving sleep disorders and slowing down disease progression. Future research should focus on the molecular mechanisms of the interaction between sleep disorders and inflammation to provide a theoretical basis for the development of more precise and effective intervention measures. In clinical treatment, it is recommended to incorporate the treatment of sleep disorders and inflammation into a comprehensive treatment plan to improve patients’ quality of life and to reduce disease risks.

Key words: sleep disorders, inflammation, correlation study

中图分类号:

R36
Q428

王琪, 王哲, 王越晖. 炎症与睡眠障碍的研究进展[J]. 实用老年医学, 2025, 39(6): 543-546.

WANG Qi, WANG Zhe, WANG Yuehui. Research progress on inflammation and sleep disorders[J]. Practical Geriatrics, 2025, 39(6): 543-546.

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