实用老年医学 ›› 2025, Vol. 39 ›› Issue (7): 719-722.doi: 10.3969/j.issn.1003-9198.2025.07.014

• 临床研究 • 上一篇    下一篇

老年高血压合并直立位低血压病人的临床特点

葛维莹, 梁颖慧, 陈一文, 郭英, 吉彤, 崔瑶, 王国宏, 刘谦   

  1. 100730 北京市,首都医科大学附属北京同仁医院老年医学科
  • 收稿日期:2024-08-27 出版日期:2025-07-20 发布日期:2025-07-22
  • 通讯作者: 刘谦,Email:13522159740@163.com

Clinical characteristics of orthostatic hypotension in elderly patients with hypertension

GE Weiying, LIANG Yinghui, CHEN Yiwen, GUO Ying, JI Tong, CUI Yao, WANG Guohong, LIU Qian   

  1. Department of Geriatrics, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China
  • Received:2024-08-27 Online:2025-07-20 Published:2025-07-22
  • Contact: LIU Qian, Email: 13522159740@163.com

摘要: 目的 探讨老年高血压合并直立位低血压(OH)病人的临床特点,为加强此类病人的管理提供依据。 方法 纳入2023年9月至2024年5月在北京同仁医院老年医学科门诊就诊及住院的高血压病人共115例,对其进行卧位和立位血压测量。根据有无OH,将病人分为高血压合并OH组(36例)和高血压无OH组(79例)。收集并比较2组一般资料、共病、用药情况及营养相关指标,记录有无直立位不耐受症状。 结果 115例老年高血压病人中,OH总体患病率为31.3%,门诊病人患病率为20.0%(8/40),住院病人患病率为37.3%(28/75)。高血压合并OH组存在直立位不耐受症状者占13.9%。高血压合并OH组病人脑血管病、外周动脉疾病、应用抗抑郁药的比例高于高血压无OH组,血清白蛋白水平低于高血压无OH组,差异均有统计学意义(P<0.05)。 结论 脑血管病和周围动脉疾病、应用抗抑郁药、低白蛋白水平可能与老年高血压病人发生OH有关。

关键词: 老年人, 高血压, 直立位低血压, 临床特点

Abstract: Objective To explore the clinical characteristics of orthostatic hypotension(OH) in the elderly patients with hypertension, so as to provide evidence for the patient management. Methods A total of 115 cases of hypertension admitted to Department of Geriatrics,Beijing Tongren hospital were enrolled from September 2023 to May 2024. The supine blood pressure and orthostatic blood pressure of the patients were measured to diagnose OH, and the orthostatic intolerance symptoms were recorded. The general information, comorbidities, medication history and nutrition indicators of the patients were collected and compared. Results The overall prevalence of OH was 31.3% (36/115), and the prevalence of outpatients was 20.0% (8/40), and the prevalence of inpatients was 37.3% (28/75). The proportion of the patients with hypertension combined with orthostatic intolerance symptoms was 13.9%. Compared with the patients without OH, the proportion of cerebrovascular disease,peripheral artery disease, and antidepressant use was higher, and the serum albumin level was lower in the patients with hypertension combined with OH (P<0.05). Conclusions Cerebrovascular disease, peripheral arterial disease, antidepressants use and low level of albumin may be associated with OH in the elderly patients with hypertension.

Key words: aged, hypertension, orthostatic hypotension, clinical characteristics

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