绝对握力与相对握力对老年结直肠癌病人术后并发症的预测价值

doi:10.3969/j.issn.1003-9198.2024.03.025

Abstract

Abstract: Objective To investigate the predictive value of absolute and relative grip strength for postoperative complications in the elderly patients with colorectal cancer. Methods A total of 268 elderly patients who underwent elective radical surgery for colorectal cancer in Jiangsu Province Hospital from September 2022 to April 2023 were enrolled in this study. The clinical data including general information, absolute grip strength, relative grip strength (grip strength to weight ratio, grip strength to BMI ratio) and occurrence of complications were collected. Univariate analysis and Logistic regression were used to explore the association between absolute and relative grip strength with postoperative complications. Receiver operating characteristic (ROC) curves were plotted to analyze the ability of absolute and relative grip strength to predict the postoperative complications in the elderly patients who underwent elective radical surgery for colorectal cancer. Results There were significant differences in age, number of drug taken, number of chronic disease, absolute grip strength and relative grip strength between the comorbidity group and non-comorbidity group. The results of Logistic regression showed that low absolute grip strength (classified by guideline or by quartile), low grip strength to weight ratio and low grip strength to BMI ratio were the independent influencing factors of complications, with odd ratio (OR) and 95%CI of 2.825 (1.436-5.557), 3.393 (1.693-6.803), 2.371 (1.210-4.647), and 2.112 (1.074-4.154), respectively. The results of ROC analysis showed that both absolute and relative grip strength (grip strength/weight, grip strength/BMI) were effective in predicting the occurrence of postoperative complications with an AUC of approximately 0.63-0.65, and in male patients, the predictive efficacy of absolute and relative strength was even higher with an AUC of approximately 0.70. Conclusions Both absolute and relative grip strength (grip strength/weight, grip strength/BMI) have a predictive value for postoperative complications in the elderly patients with colorectal cancer. Grip strength assessment can be included in the preoperative evaluation for the elderly patients with colorectal cancer.

Key words: grip strength, aged, colorectal cancer, complication, predictive value

CLC Number:

YAO Cui, DING Lingyu, HU Jieman, SUN Yueming. Predictive value of absolute and relative grip strength for postoperative complications in elderly patients with colorectal cancer[J]. Practical Geriatrics, 2024, 38(3): 317-321.

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Predictive value of absolute and relative grip strength for postoperative complications in elderly patients with colorectal cancer

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