Practical Geriatrics ›› 2024, Vol. 38 ›› Issue (12): 1242-1245.doi: 10.3969/j.issn.1003-9198.2024.12.012

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Effect of serratus anterior plane block on inflammatory factors in elderly patients undergoing thoracoscopic surgical ablation for atrial fibrillation

XU Peilong, WANG Min, CHEN Yu, CHEN Xiaodong   

  1. Department of Anesthesiology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China
  • Received:2024-06-03 Online:2024-12-20 Published:2024-12-19
  • Contact: CHEN Xiaodong, Email: xiaodongc_xy@aliyun.com

Abstract: Objective To evaluate the effect of ultrasound-guided serratus anterior plane block (SAPB) combined with general anesthesia on postoperative inflammatory factors in the elderly patients undergoing thoracoscopic surgical ablation for atrial fibrillation. Methods This study was a single-center, prospective, randomized controlled trial involving 80 elderly patients, who were randomly divided into SAPB group and control group. The SAPB group received preoperative ultrasound-guided bilateral SAPB (20 mL of 0.375% ropivacaine on each side), while the control group did not receive nerve block. The levels of the inflammatory factors within 24 hours after the operation were compared between the two groups. Results The levels of interleukin-6 (IL-6) and high sensitivity C-reaction protein (hs-CRP) in the SAPB group were significantly lower than those in the control group (P<0.01). The SAPB group showed more stable postoperative vital signs and significantly lower pain scores compared to the control group (P<0.01). Conclusions SAPB combined with general anesthesia can effectively reduce postoperative inflammation in the elderly patients undergoing thoracoscopic surgical ablation for atrial fibrillation, and improve the postoperative recovery.

Key words: nerve block, atrial fibrillation, inflammatory factor, aged, surgical ablation

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