Practical Geriatrics ›› 2021, Vol. 35 ›› Issue (7): 727-730.doi: 10.3969/j.issn.1003-9198.2021.07.016

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Cognitive frailty and its influencing factors in hospitalized elderly patients with hypertension

YAN Jing, CHEN Xin-tao, MO Dong-ni, WU Zhu-jie, MA Li, HUANG Li-ting, LIU Ying   

  1. General Practice Department, the First People's Hospital of Nanning, Nanning 530022, China
  • Received:2020-08-25 Online:2021-07-20 Published:2021-08-02

Abstract: Objective To investigate the prevalence of cognitive frailty and its influencing factors and to provide evidence for early evaluation and intervention of cognitive frailty in the elderly patients with hypertension. Methods The clinical data of 106 elderly patients with hypertension hospitalized in our hospital from January to October 2019 were enrolled. Fried standard was used to evaluate the state of frailty, and Mini-Mental State Examination scale (MMSE) was used to evaluate the cognitive status of patients. The patients with frailty and cognitive impairment were defined as cognitive frailty. A total of 106 hospitalized elderly patients with hypertension were divided into cognitive frailty group (n=26) and non-cognitive frailty group (n=80).The general demographic data, geriatric syndrome and chronic disease history of the two groups were observed and analyzed. Multivariate Logistic regression was used to analyze the independent related factors of cognitive frailty. Results The incidence of hypertension complicated with cognitive frailty in the elderly was 24.5%. The age in the cognitive frailty group was older and the third grade of hypertension was more common than that in the non-cognitive frailty group (P<0.01). The ratio of malnutrition or the risk of malnutrition, falls, chronic pain, multiple drugs, coronary heart disease, type 2 diabetes and chronic kidney disease in the cognitive frailty group were significantly higher than those in the non-cognitive frailty group (P<0.05). Multivariate Logistic regression analysis showed that the age(OR=7.828,95%CI:1.558-39.321), malnutrition or the risk of malnutrition (OR=20.364,95%CI:3.724-111.346)and chronic kidney disease (OR=5.699,95%CI:1.172-27.716)were the independent risk factors of cognitive frailty in the elderly patients with hypertension (all P<0.05). Conclusions The incidence of cognitive frailty in the elderly patients with hypertension is higher. Age, malnutrition or the risk of malnutrition and chronic kidney disease are the independent related factors of cognitive frailty in the elderly patients with hypertension.

Key words: aged, hypertension, cognitive frailty

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