Abstract: Objective To investigate the risk factors for re-fracture after osteoporotic fracture in the elderly women. Methods A retrospective analysis of 85 elderly women with osteoporotic fractures admitted to our hospital from September 2018 to January 2020 were divided into re-fracture group(n=45) and new fracture group (n=40). The basic data and clinical data of the two groups were compared, and the risk factors of re-fracture after osteoporotic fracture were analyzed by multivariate Logistic regression analysis. Results There were significant difference in the age, body mass index (BMI), bone mineral density(BMD), transition time from supine to standing position and total alkaline phosphatase(TALP) between the two groups (P<0.05). Multivariate Logistic regression analysis showed that the risk factors for re-fracture after osteoporotic fracture in the elderly women were age ≥75 years (OR=1.612, 95%CI: 1.129-8.994), BMI ≤21.00 (OR=1.725, 95%CI: 1.160-5.338), T value of BMD＜-3.50 (OR=2.125, 95%CI: 1.815-4.888), the transition time from supine to standing position≥20 s (OR=1.688, 95%CI: 1.009-3.228) and TALP≥110.00 μg/L (OR=1.123, 95%CI: 1.015-2.177). Conclusions Older, less BMI and BMD, longer transition time from supine to standing position, and increased TALP level are the independent risk factors of re-fractures after osteoporotic fractures in the elderly women.

Key words: elderly women, osteoporosis, re-fracture, risk factor