衰弱在老年冠心病病人久坐行为与生活质量间的中介效应分析

doi:10.3969/j.issn.1003-9198.2024.12.018

Abstract

Abstract: Objective To investigate the relationship between sedentary behavior, frailty, and quality of life in the elderly patients with coronary heart disease. Methods A total of 264 elderly patients from Cardiology Outpatient Department in Ruijin Hospital were enrolled in the study. The basic data were collected with a general information questionnaire, and the sedentary behavior, frailty, and quality of life were assessed with Chinese Adult Sedentary Behavior Questionnaire, frailty scale, and European Quality of Life-5 Dimensions(EQ-5D), respectively. Spearman correlation analysis was used to analyze the correlation between sedentary behavior, frailty and quality of life, and the mediating effect of frailty between sedentary behavior and quality of life in the elderly patients with coronary artery disease was analyzed using SPSS macro program PROCESS 4.1 test, and the Bootstrap method was used to test the significance of the mediating effect. Results The elderly patients with coronary heart disease had an average daily sedentary behavior time of 6.5 (4.7, 8.5) hours. Among them, 58 patients (22.0%) presented with frailty, and 120 patients (45.4%) presented with pre-frailty. The score of frailty scale was 1.00 (0.00, 2.00), and the score of EQ-5D was 1.00 (0.87, 1.00). The duration of sedentary behavior was negatively correlated with the score of quality of life (r=-0.596), and positively correlated with the score of frailty scale (r=0.552), and the score of frailty scale was negatively correlated with the score of quality of life (r=-0.744). The direct effect of sedentary behavior on quality of life was -0.488, and the mediating effect was -0.309, with 95%CI of (-0.381, -0.244). The total effect was -0.797, and the proportion of the intermediate effect to the total effect was 38.77%. Conclusions Frailty plays a partial mediating role between sedentary behavior and quality of life in the elderly patients with coronary heart disease. Consequently, it is crucial to focus on both sedentary behavior and frailty to improve the quality of life of the elderly patients.

Key words: coronary artery disease, quality of life, frailty, sedentary behavior, aged

CLC Number:

JIANG Yulu, XIN Xiao, NI Xueping, CUI Peirong, WANG Qingqing, HUANG Wenni, QIN Shiyu, LI Xianhua. Analysis of the mediating effect of frailty on the relationship between sedentary behavior and quality of life in elderly patients with coronary heart disease[J]. Practical Geriatrics, 2024, 38(12): 1270-1274.

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Analysis of the mediating effect of frailty on the relationship between sedentary behavior and quality of life in elderly patients with coronary heart disease

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