Practical Geriatrics ›› 2023, Vol. 37 ›› Issue (7): 719-722.doi: 10.3969/j.issn.1003-9198.2023.07.017

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Effect of high flux hemodialysis and hemodiafiltration on the quality of life in elderly patients receiving maintenance hemodialysis

XIE Qing-lei, ZHANG Liu-ping, WANG Yue   

  1. Blood Purification Center, Zhongda Hospital, Southeast University, Nanjing 210009, China
  • Received:2022-09-29 Online:2023-07-20 Published:2023-07-25
  • Contact: ZHANG Liu-ping, Email: shery9926@sina.com

Abstract: Objective To investigate the effects of hemodiafiltration (HDF) and high flux hemodialysis ( HFHD) on the quality of life(QOL) in the elderly patients receiving maintenance hemodialysis(MHD). Methods A cross-sectional study was conducted in Blood Purification Center, Zhongda Hospital, Southeast University from January 2019 to December 2021, and the clinical data of all patients were collected. Kidney disease quality of life-short form (KDQOL-SF) was applied to assess the health-related quality of life (HRQL) of the patients. The efficacy and QOL were compared between the patients receiving HFHD and those receiving HDF after propensity score matching(PSM). Results There were significant differences in scores of burden of kidney disease in kidney disease-targeted areas (KDTA) and scores of physical functioning, general health, and vitality of 36-item health survey (SF-36) (P<0.05). Conclusions In elderly MHD patients, disease burden caused by HDF is heavier than HFHD, but HDF can improve QOL -related physiological functions, general health and vitality.

Key words: hematodialysis, aged, quality of life, Kidney disease quality of life-short form questionnaire, propensity score

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