左心房存储应变对老年心力衰竭病人远期不良预后的预测价值

doi:10.3969/j.issn.1003-9198.2022.10.014

Abstract

Abstract: Objective To explore the predictive value of left atrial strain for the long-term poor prognosis of elderly patients with heart failure. Methods A total of 136 elderly patients with heart failure age ≥ 65 years old admitted to Chengde Central Hospital from July 2018 to July 2019 were prospectively selected as the research subjects. The patients were followed up for 2 years. According to the all-cause death results, they were divided into poor prognosis group and good prognosis group. The influencing factors of long-term poor prognosis of the elderly patients with heart failure were analyzed by multivariate Cox regression. Results By the end of the follow-up, 42 cases (33.60%) presented with all-cause death and 83 cases (66.40%) with a good prognosis. There were significant differences in the levels of left atrial volume index (LAVI), left atrial reserve strain (LARS), left ventricular ejection fraction (LVEF) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) between poor prognosis group and good prognosis group. Multivariate Cox regression analysis showed that NT-proBNP (HR=1.001, 95%CI: 1.000-1.002) and LAVI (HR=1.082, 95%CI:1.002-1.168) were the independent risk factors of long-term poor prognosis, and LVEF (HR=0.944, 95%CI:0.893-0.998) and LARS (HR=0.945, 95%CI:0.902-0.991) were the protective factors of long-term poor prognosis in the elderly patients with heart failure (all P<0.05). ROC curve analysis showed that the area under curve(AUC) of LARS was higher than that of LVEF and LAVI. Conclusions LAVI, LARS, LVEF and NT-proBNP can predict the long-term poor prognosis of elderly patients with heart failure, and LARS is more valuable than other parameters.

Key words: left atrial strain, heart failure, aged, prognosis

CLC Number:

R541.61

MA Xiao-ying, LI Jiu-min, QIN Pei, LIU Miao, JIN Ming-lei. Predictive value of left atrial strain for long-term poor prognosis of elderly patients with heart failure[J]. Practical Geriatrics, 2022, 36(10): 1033-1037.

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Predictive value of left atrial strain for long-term poor prognosis of elderly patients with heart failure

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