Practical Geriatrics ›› 2022, Vol. 36 ›› Issue (9): 911-915.doi: 10.3969/j.issn.1003-9198.2022.09.011

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Predictive value of prognostic nutritional index for the prognosis of elderly patients with severe chronic obstructive pulmonary disease

YANG Jun-hong, LIANG Lan-yu, SHAN Qing   

  1. YANG Jun-hong. Medical College of Yangzhou University, Yangzhou 225000, China;
    LIANG Lan-yu, SHAN Qing. Department of Geriatrics, Affiliated Hospital of Yangzhou University, Yangzhou 225000, China
  • Received:2021-10-13 Online:2022-09-20 Published:2022-09-21

Abstract: Objective To explore the predictive value of prognostic nutritional index (PNI) for the prognosis of the elderly patients with severe chronic obstructive pulmonary disease(COPD). Methods A retrospective analysis of the clinical data of 132 elderly patients with severe COPD who were admitted into the Affiliated Hospital of Yangzhou University from January 2016 to December 2019 was conducted. The receiver operator characteristic (ROC) curve was used to analyze the correlation between PNI and the prognosis. The patients were divided into a death group and a survival group according to the survival 6 months later, and the differences in the levels of the clinical indicators were compared between the two groups. COX regression model and Kaplan-Meier curve were used to explore the relationship between PNI and the prognosis of the elderly patients with severe COPD. Results A total of 132 patients were included, with 72 cases in the death group and 60 cases in the survival group. The best cut-off value of PNI was 37.32. Multivariate COX regression analysis indicated that age, PNI<37.32 and total hospital stay were the independent prognostic factors for death in the elderly patients with severe COPD. Conclusions PNI shows predictive value for the prognosis of the elderly patients with severe COPD, and PNI<37.32 indicates poor survival.

Key words: chronic obstructive pulmonary disease, prognostic nutritional index, aged, nutritional evaluation, prognosis

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