利多卡因气雾剂在老年病人无痛胃镜诊疗中的应用

doi:10.3969/j.issn.1003-9198.2024.03.012

Abstract

Abstract: Objective To observe the safety and effectiveness of lidocaine aerosol in painless gastroscopy in the elderly patients. Methods A total of 100 patients over 65 years old with American Society of Anesthesiologists classificationⅠ-Ⅲ in our endoscopy center receiving painless gastroscopy from June to December 2022 were divided into two groups (n=50) according to random number table. The patients in group A received lidocaine aerosol sprayed to the surface of throat, followed by intravenous anesthesia with remifentanil and propofol, while the patients in group B were directly intravenously anesthetized with remifentanil and propofol. The preoperative and the lowest intraoperative mean arterial pressure (MAP), heart rate (HR) and pulse oxygen saturation (SpO₂) in the two groups were recorded and compared. The dosage during successful implantation of gastroscope and total amount of propofol, the Ramsay sedation score and recovery time, the incidence of intraoperative adverse reactions, including coughing, motility, respiratory depression (SpO₂<90%), hypotension (<30% of the baseline value) and decreased HR (<50 beats/min) were recorded and compared between the two groups. Results Compared with group B, the dosage during successful implantation of gastroscope and total amount of propofol were significantly decreased (P<0.05). The intraoperative minimum MAP, HR and SpO₂ were significantly increased (P<0.05), and the Ramsay sedation score and recovery time were significantly decreased (P<0.05). The incidence rates of adverse reactions of coughing, respiratory depression and hypotension were significantly reduced (P<0.05) in group A. Conclusions Lidocaine aerosol can significantly reduce the amount of propofol. At the same time, the adverse reactions of coughing, respiratory depression, hypotension and decreased heart rate are also significantly reduced. Besides, the patients receiving lidocaine aerosol present with a shorter wake-up time. Thus, lidocaine aerosol is a safe and effective anesthesia method suitable for painless gastroscopy in the elderly patients.

Key words: lidocaine aerosol, aged, painless gastroscope

CLC Number:

LIU Xiangrong, SONG Shaobo, LIU Sheng'an, LI Hui, CHEN Guosheng. Application of lidocaine aerosol in painless gastroscopy in elderly patients[J]. Practical Geriatrics, 2024, 38(3): 265-269.

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Application of lidocaine aerosol in painless gastroscopy in elderly patients

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