老年前降支单支病变冠心病病人经皮冠状动脉介入治疗术后运动耐量的影响因素分析

doi:10.3969/j.issn.1003-9198.2021.09.018

Abstract

Abstract: Objective To investigate the influencing factors of exercise tolerance in the elderly patients with single vessel lesion of anterior descending coronary artery after percutaneous coronary intervention (PCI). Methods The clinical data of 126 elderly patients with single vessel lesion of anterior descending coronary artery in our hospital from May 2018 to November 2019 were retrospectively analyzed. According to the exercise tolerance after PCI,the patients were divided into the exercise tolerance decreased group and the exercise tolerance normal group. The influencing factors of exercise tolerance in the elderly patients with single vessel lesion of anterior descending coronary artery after PCI were analyzed by multivariate Logistic regression analysis. The patients were followed up for 1 year after PCI, and the incidence rate rate of major adverse cardiovascular events was compared between the two groups. Results The incidence rate of reduced exercise tolerance in the elderly patients with single vessel lesion of anterior descending coronary artery after PCI was 54.76% (69/126).Compared with the normal exercise tolerance group, the levels of left ventricular ejection fraction (LVEF) and peak oxygen uptake (VO_2peak) in the reduced exercise tolerance group decreased, the levels of body mass index (BMI), heart rate, left atrial anteroposterior diameter (LAAD) and N-terminal B-type pro-brain natriuretic peptide (NT-proBNP) in the exercise tolerance group increased. And the composition ratios of diabetes, history of myocardial infarction, and perioperative myocardial injury in the exercise tolerance decreased group were significantly higher than those in the normal exercise tolerance group (P＜0.05). Multivariate Logistic regression analysis showed that combined with diabetes, history of myocardial infarction, perioperative myocardial injury and VO_2peakwere independent influencing factors of exercise tolerance in the elderly patients with single vessel lesion of anterior descending coronary artery after PCI. One year after PCT, there was no significant difference in the total incidence of major adverse cardiovascular events between the two groups (P>0.05). Conclusions Diabetes mellitus, history of myocardial infarction, perioperative myocardial injury and VO₂_peak are influencing factors of exercise tolerance in the elderly patients with single vessel lesion of anterior descending coronary artery after PCI.

Key words: aged, coronary heart disease, percutaneous coronary intervention, exercise tolerance, influencing factor

CLC Number:

R 541.4

LIU Hong-qiang, ZHANG Hong-lei, ZHENG Xiao-hui. Influencing factors of exercise tolerance in elderly patients with single vessel lesion of anterior descending coronary artery after percutaneous coronary intervention[J]. Practical Geriatrics, 2021, 35(9): 967-970.

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Influencing factors of exercise tolerance in elderly patients with single vessel lesion of anterior descending coronary artery after percutaneous coronary intervention

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