Abstract: Objective To analyze the correlation between platelet parameters and blood pressure in the elderly. Methods The clinical data of 1023 elderly patients in Tianyou Hospital Affiliated to Tongji University from January 2016 to August 2019 were collected. According to the level of blood pressure, they were divided into three groups: normotension group (＜120/80 mmHg, n=215), prehypertension group [(120-139)／(80-89) mmHg,n=531] and hypertension group (≥140／90 mmHg,n=277). The correlation between platelet parameters and blood pressure was analyzed. Results The levels of mean platelet volume (MPV) and platelet distribution width (PDW) in hypertension group and prehypertension group were higher than those in normotension group (P<0. 05), but platelet count (PLT) and platelet thrombocytocrit (PCT) showed no significant difference among the three groups. Spearman correlation analysis showed that MPV and PDW were positively correlated with systolic blood pressure (SBP) (P<0. 01); PLT and PCT were not correlated with SBP (P＞0. 05); MPV, PDW, PLT and PCT were not correlated with diastolic blood pressure (DBP) (P＞0. 05). The multiple linear regression analysis showed that MPV was an independent factor of SBP (P<0. 01). All the elderly were divided into Q1-Q4 groups according MPV quartile division. Logistic regression analysis showed that the risk of hypertension in Q4 group was 1. 529 times of that in Q1 group (95％CI:1. 106-2. 319,P<0. 05) after adjusting for gender, age, height, body weight, body mass index, waist circumference, hip circumference, waist-to-hip ratio, total cholesterol, triglyceride, low-density lipoprotein cholesterol, creatinine, alanine aminotransferase, fasting blood glucose, smoking and drinking. Conclusions Platelet parameters are closely related to blood pressure in the elderly, elevated MPV may be associated with the occurrence and development of hypertension.

Key words: aged, platelet parameter, hypertension