基于老年综合评估的2型糖尿病病人衰弱影响因素分析

doi:10.3969/j.issn.1003-9198.2022.12.019

Abstract

Abstract: Objective To analyze the influencing factors of frailty in the elderly patients with type 2 diabetes mellitus (T2DM) by comprehensive geriatric assessment. Methods A total of 210 patients with T2DM aged ≥ 65 years old who were hospitalized in the Department of Geriatric Endocrine of Jiangsu Province Hospital from January 2020 to June 2021 were enrolled and divided into frailty group and non-frailty group according to the results of Physical Frailty Phenotype(PFP). The status of nutrition, cognition, psychology, prognosis and physical function of the patients were measured by Mini Nutritional Assessment Scale (MNA), Mini-mental State Examination (MMSE), Geriatric Depression Scale (GDS), Multidimensional Prognostic Index (MPI) score for inpatients, 4 m walking speed, Timed Up and Go (TUG) test, TUG manual (TUGman), TUG cognitive (TUGcog), respectively. Binary Logistic regression analysis was used to analyze the influencing factors of frailty in the hospitalized elderly patients with T2DM. Results There were significant differences in gender, age, marital status, residential status, course of disease, nutritional status, cognitive status, psychological status, risk of death, risk of fall, walking speed, TUG, glycated hemoglobin, body mass index and grip strength between two groups(P<0.05). Binary Logistic regression analysis showed that female, long course of diabetes, low grip strength and low 4 m walking speed were the risk factors of frailty in the hospitalized elderly patients with T2DM. Conclusions The assessment of frailty in the elderly patients with T2DM needs to be diversified. The comprehensive geriatric assessment method for the elderly can be used to investigate the influencing factors of frailty in the elderly patients with T2DM and improve the quality of life.

Key words: aged, diabetes, frailty, comprehensive geriatric assessment

CLC Number:

R587.1

BAO Hai-tong, TAN Ping, YU Pei-wen, LIU Juan, DING Guo-xian, TONG Qiang-wei, WANG Xiao-dong. Analysis of influencing factors of frailty based on geriatric comprehensive assessment in the elderly patients with type 2 diabetes mellitus[J]. Practical Geriatrics, 2022, 36(12): 1264-1268.

References

[1] KHAN S S, SINGER B D, VAUGHAN D E. Molecular and physiological manifestations and measurement of aging in humans[J]. Aging Cell, 2017, 16(4):624-633.
[2] WILKINSON D J, PIASECKI M, ATHERTON P J. The age-related loss of skeletal muscle mass and function: measurement and physiology of muscle fibre atrophy and muscle fibre loss in humans[J]. Ageing Res Rev, 2018,47:123-132.
[3] 刘娟,丁国宪.老年人失能专家论坛:老年人肌少症与失能[J]. 中华老年医学杂志, 2019, 38(10):1091-1093.
[4] CESARI M, CALVANI R, MARZETTI E. Frailty in older persons[J]. Clin Geriatr Med, 2017, 33(3):293-303.
[5] ENSRUD K E, KATS A M, SCHOUSBOE J T, et al. Frailty phenotype and healthcare costs and utilization in older women[J]. J Am Geriatr Soc, 2018, 66(7):1276-1283.
[6] 张秀锦,刘宏斌.老年综合评估技术在心血管科的应用前景[J].中华保健医学杂志, 2021, 23(1):108-110.
[7] ALBERTI K G, ZIMMET P Z. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1:diagnosis and classification of diabetes mellitus provisional report of a WHO consultation[J]. Diabet Med,1998,15(7):539-553.
[8] HUANG C H, OKADA K, MATSUSHITA E, et al. Sex-specific association between social frailty and diet quality, diet quantity, and nutrition in community-dwelling elderly[J]. Nutrients, 2020, 12(9):2845.
[9] GUIGOZ Y,VELLAS B, GARRY P J. Assessing the nutritional status of the elderly: the Mini Nutritional Assessment as part of the geriatric evaluation[J]. Nutr Rev,1996,54(1 Pt 2):S59-S65.
[10] GIEBEL C M, CHALLIS D. Sensitivity of the Mini-Mental State Examination, Montreal Cognitive Assessment and the Addenbrooke's Cognitive Examination III to everyday activity impairments in dementia: an exploratory study[J]. Int J Geriatr Psychiatry, 2017, 32(10):1085-1093.
[11] ACOSTA QUIROZ C O, GARCÍA-FLORES R, ECHEVERRÍA-CASTRO S B. The Geriatric Depression Scale (GDS-15): validation in Mexico and disorder in the state of knowledge[J]. Int J Aging Hum Dev, 2021, 93(3):854-863.
[12] CUNHA A I L, VERONESE N, DE MELO BORGES S, et al. Frailty as a predictor of adverse outcomes in hospitalized older adults: a systematic review and meta-analysis[J]. Ageing Res Rev, 2019, 56:100960.
[13] 王欣,王宏,许蕊凤,等.Morse跌倒风险评估模型对预测足踝外科手术后跌倒的风险度分级探讨及跌倒危险因素分析[J]. 足踝外科电子杂志, 2021, 8(1):11-15.
[14] OFORI ASENSO R, CHIN K L, MAZIDI M, et al. Global incidence of frailty and prefrailty among community-dwelling older adults: a systematic review and meta-analysis[J]. JAMA Netw Open, 2019, 2(8):e198398.
[15] 朱新蕊,孔翎宇,林丽珍,等.性别及相关因素影响人体衰弱的研究进展[J]. 中国老年保健医学,2022, 20(3):85-88.
[16] 韩文璐, 张兆志, 王晓东. 老年2型糖尿病患者衰弱影响因素及对策分析[J]. 国际老年医学杂志, 2021, 42(6):350-353.
[17] HONG X, YAN J, XU L, et al. Relationship between nutritional status and frailty in hospitalized older patients[J].Clin Interv Aging, 2019, 10(14):105-111.
[18] LANDI F,CALVANI R,CESARI M, et al. Sarcopenia: an overview on current definitions, diagnosis and treatment[J]. Curr Protein Pept Sci, 2018, 19(7):633-638.
[19] 赵欧, 李耘, 张亚欣,等.住院患者社会衰弱情况及影响因素分析[J]. 北京医学, 2021, 43(8):730-734.
[20] HOWREY B T, AL SNIH S, MARKIDES K S, et al. Frailty and diabetes among Mexican American older adults[J]. Ann Epidemiol, 2018, 28 (7):421-426.

Analysis of influencing factors of frailty based on geriatric comprehensive assessment in the elderly patients with type 2 diabetes mellitus

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