颈动脉斑块和ABI协同预测老年人群远期新发心脑血管不良事件临床价值探讨

doi:10.3969/j.issn.1003-9198.2022.10.012

Abstract

Abstract: Objective To investigate the clinical value of carotid plaque combined with ankle branchial index (ABI) in predicting long-term new cardiovascular and cerebrovascular adverse events in the elderly. Methods A total of 821 elderly subjects participating in physical examination and receiving carotid ultrasound and ABI examination from January 2013 to January 2015 in our hospital were enrolled. All patients were divided into 3 groups, group A with no carotid plaque and ABI>0.9, group B with carotid plaque and ABI>0.9, and group C with carotid plaque and ABI≤0.9. The clinical characteristics and cardiovascular and cerebrovascular events were compared among the groups. Multivariate Cox proportional hazard model was used to evaluate the value of carotid plaque combined with ABI level in predicting the risk of long-term ischemic cardiovascular and cerebrovascular events. Results There were significant differences in age, gender, smoking and drinking ratio, systolic blood pressure (SBP), fasting plasma glucose (FPG), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C) and the proportion of receiving lipid-lowering drugs among the three groups (P<0.05). There were significant differences in the incidence rates of ischemic cardiovascular and cerebrovascular events and acute myocardial infarction (AMI) among the three groups(P<0.05). Univariate analysis of Cox proportional risk model showed that the risk of long-term ischemic cardio-cerebrovascular events, AMI and cerebral infarction in group B and group C were significantly higher than those in group A(P<0.05). Multivariate Cox proportional hazards model analysis showed that the risk of long-term ischemic cardiovascular and cerebrovascular events in group B and group C was 4.76 times(HR=4.76,95%CI:1.32-7.07),8.51 times(HR=8.51,95%CI:1.65-11.80) of that in group A after adjusting for age, gender, smoking and alcohol consumption, SBP, FPG, LDL-C, HDL-C and treatment with lipid-lowering drugs(P<0.05). Conclusions The elderly population with carotid plaque and ABI ≤ 0.9 are more likely to present with long-term new cardiovascular and cerebrovascular adverse events.

Key words: aged, carotid plaque, ankle brachial index, myocardial infarction, cerebral infarction

CLC Number:

R743.3

FENG Wei-tao, LI Yao, LI Wei. Clinical value of carotid plaque combined with ABI in predicting long-term new cardiovascular and cerebrovascular adverse events in elderly[J]. Practical Geriatrics, 2022, 36(10): 1024-1027.

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Clinical value of carotid plaque combined with ABI in predicting long-term new cardiovascular and cerebrovascular adverse events in elderly

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