Abstract: Objective To explore the status and influencing factors of intrinsic capacity (IC) in the elderly patients receiving maintenance hemodialysis (MHD), and to provide evidence for improving the quality of life. Methods Convenience sampling was used to select the elderly MHD patients from the outpatient department of Blood Purification Center of Zhongda Hospital Southeast University from January to June 2023. The general information and clinical data of the patients were collected. The level of IC was evaluated, including the Short Physical Performance Battery(SPPB), Mini Nutritional Assessment short-form(MNA-SF), Mini-Mental State Examination (MMSE), Zung’s Self-rating Depression Scale and self-reported visual/hearing impairment. Results A total of 175 elderly MHD patients were enrolled in this study, with an average age of 69.78±6.92 years, with an average dialysis age of 66.91±55.36 months. Among them, there were 105 males (60.00%), 53 cases (30.29%) with good IC (≥ 3 points) and 122 cases (69.71%) with poor IC (<3 points). The total average score of IC was 2.25±1.03 points. Multiple Logistic regression analysis showed that albumin was a protective factor, and age and β2-microglobulin were independent risk factors for IC in the elderly MHD patients. Conclusions The decline of IC is common in the elderly MHD patients, and high level of albumin could improve the level of IC in the patients.

Key words: aged, maintenance hemodialysis, intrinsic capacity, influencing factor