术前HALP评分对老年非小细胞肺癌手术病人预后的预测价值

doi:10.3969/j.issn.1003-9198.2022.12.018

Abstract

Abstract: Objective To investigate the predictive value of preoperative hemoglobin, albumin, lymphocyte and platelet (HALP) score for the prognosis of the elderly patients with non-small cell lung cancer (NSCLC) undergoing surgery. Methods The clinical data of 270 elderly patients with NSCLC undergoing surgery in Xinxiang Central Hospital from January 2015 to December 2019 were collected, and the predictive value of HALP score for the prognosis was analyzed. Results Univariate Cox regression analysis showed that preoperative HALP score, ΔHALP score, tumor TNM stage, tumor differentiation, smoking history, tumor location, serum albumin level, hemoglobin level and postoperative hospital stay were associated with postoperative overall survival (OS) and progression-free survival (PFS) (all P<0.05). Multivariate Cox regression analysis showed that preoperative HALP score, tumor TNM stage and tumor differentiation were the independent risk factors for OS and PFS, and preoperative serum albumin level was an independent risk factor for OS (all P＜0.05). Conclusions HALP score can be used as a predictor for postoperative survival in the elderly patients with NSCLC after surgery, which could assist clinical targeted intervention to improve prognosis.

Key words: aged, non-small cell lung cancer, nutrition, inflammation, immunity, HALP score

CLC Number:

R734.2

YUAN Meng-yi, WANG Pei-shan, MENG Rui-xia, YANG Jian-jun, ZHOU Cheng-mao, JIAO Zhong-yu. Predictive value of preoperative hemoglobin, albumin, lymphocyte and platelet(HALP) score for prognosis of elderly patients with non-small cell lung cancer undergoing surgery[J]. Practical Geriatrics, 2022, 36(12): 1259-1263.

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Predictive value of preoperative hemoglobin, albumin, lymphocyte and platelet(HALP) score for prognosis of elderly patients with non-small cell lung cancer undergoing surgery

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