Abstract: Objective To explore the construction and application of the early warning score scale for respiratory failure in the elderly patients with early lung cancer. Methods The clinical data of 126 elderly patients with early lung cancer treated in our hospital from October 2018 to January 2020 were analyzed. They were divided into respiratory failure group (n=40) and the control group (n=86). Univariate and multivariate analysis were performed to identify the risk factors of respiratory failure and early warning score scale was established according to the results. Results Multivariate regression results suggested that age>75 years old, urban residence, smoking>400 cigarettes/year, maximum chase gas volume (MVV) < 60%, ratio of residual air volume to total lung volume (RV/TLC)> 50%, forced expiratory volume in 1s(FEV1)< 1.5 L, ventilation reserve (VR) <85% were risk factors of respiratory failure in the elderly patients with early lung cancer. The constructed early warning score scale was applied in the past 534 case, and the subjects were divided into 4 groups according to the interquartile range, and the ratio of the actual respiratory failure incidence rate(O) and the predicting respiratory failure incidence rate(E) of each risk group was calculated. The O/E ratio was 0.52-0.93 with the increase of the early warning scores. Conclusions The early warning score can predict the occurrence of respiratory failure and can be used as a screening tool for the risk of respiratory failure in the elderly patients with early lung cancer.

Key words: lung cancer, aged, respiratory failure, early warning score scale