Abstract: Objective To investigate the clinical efficacy of cardiac intervention therapy in the elderly patients with acute myocardial infarction and the influence on inflammatory factors and ventricular remodeling. Methods A total of 88 elderly patients with acute myocardial infarction from March 2018 to March 2019 were divided into control group (n=44) and observation group (n=44). The control group was given interventional therapy, and the observation group received cardiac intervention on the basis of the control group. The effect was evaluated after 4 weeks of treatment. The levels of cardiac function, inflammatory factors, ventricular remodeling and incidence rate of cardiovascular complications were compared between the two groups. Results The level of left ventricular ejection fraction (LVEF) in the observation group was higher than that of the control group 4 weeks after treatment (P<0. 05); The levels of left ventricular end diastolic diameter (LVEDD) and left ventricular end systolic diameter (LVESD) in the observation group were lower than those in the control group (P<0. 05). The levels of the inflammatory factors including B-type natriuretic peptide (BNP), soluble apoptosis related factor (s-fas), interleukin-6 (IL-6) and high sensitivity C-reactive protein (hs-CRP) in the observation group were lower than those in the control group (P<0. 05). The incidence rate of cardiovascular complications including recurrent angina pectoris, heart failure, cardiogenic shock, arrhythmia and recurrent myocardial infarction in the observation group was lower than that in the control group(P<0. 05). Conclusions Cardiac intervention in the elderly patients with acute myocardial infarction can improve the level of cardiac function and the ventricular remodeling, and reduce the level of inflammatory factors and the incidence rate of interventional therapy complications, which is worthy of promotion and application.

Key words: cardiac intervention, acute myocardial infarction, cardiac function, ventricular remodeling, inflammatory factor, aged