Practical Geriatrics ›› 2024, Vol. 38 ›› Issue (7): 688-692.doi: 10.3969/j.issn.1003-9198.2024.07.010

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Diagnostic value of rapid on-site evaluation combined with radial probe endobronchial ultrasound transbronchial lung biopsy for peripheral pulmonary lesions in elderly patients

JIANG Ting, LI Li, WANG Yan   

  1. Department of Respiratory Medicine(JIANG Ting, LI Li); Medical Imaging Department Ⅱ(WANG Yan), the Affiliated Nanjing Brain Hospital of Nanjing Medical University, Nanjing 210029, China
  • Received:2023-11-23 Published:2024-07-23
  • Contact: WANG Yan, Email:wyyqwd@sina.com

Abstract: Objective To explore the value of rapid on-site evaluation(ROSE) during radial probe endobronchial ultrasound transbronchial lung biopsy(EBUS-TBLB) for peripheral pulmonary lesions(PPLs) in the elderly patients. Methods A total of 112 elderly patients who presented with undiagnosed PPLs by computed tomography(CT) were enrolled in this study. All patients received EBUS-TBLB examination, and biopsy specimens obtained from each operation underwent ROSE operation. The ROSE results were compared with the final pathological results, and the number of biopsies and operating time in ROSE positive group and ROSE negative group were recorded and compared. The feasibility and safety of ROSE combined with EBUS-TBLB in the the elderly patients with PPLs were analyzed. Results The diagnostic accuracy, sensitivity and specificity of ROSE combined with EBUS-TBLB for PPLs in the elderly patients were 90.2%, 86.7% and 97.3%, respectively. The number of biopsies and operating time were lower in ROSE positive group than those in ROSE negative group(All P<0.05). No serious operative complications were observed. Conclusions ROSE combined with EBUS-TBLB is a safe and effective method for diagnosing PPLs in the elderly patients.

Key words: aged, radial probe endobronchial ultrasound, transbronchial lung biopsy, rapid on-site evaluation, peripheral pulmonary lesions

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