Practical Geriatrics ›› 2024, Vol. 38 ›› Issue (7): 658-661.doi: 10.3969/j.issn.1003-9198.2024.07.003

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Analysis of risk factors of left ventricular diastolic dysfunction in elderly patients with maintenance hemodialysis

DONG Fengming, HUANG Bikun, CAO Jingyuan, CHEN Huimin, ZHANG Yu, ZHANG Liuping, ZhANG Wei   

  1. Blood Purification Center,Taizhou People's Hospital Affiliated to Nanjing Medical University,Taizhou 225300, China(DONG Fengming,CAO Jingyuan,CHEN Huimin, ZHANG Yu);
    Taizhou Vocational and Technical College,Taizhou 225300, China(HUANG Bikun);
    Blood Purification Center,Zhongda Hospital Southeast University,Nanjing 210009, China(ZHANG Liuping);
    Blood Purification Center,Taizhou Third People's Hospital, Taizhou 225300, China(ZhANG Wei)
  • Received:2024-05-04 Published:2024-07-23
  • Contact: ZHANG Wei, Email:522314537@qq.com

Abstract: Objective To explore the risk factors of left ventricular diastolic dysfunction(LVDD) in the elderly patients undergoing maintenance hemodialysis(MHD). Methods A total of 178 elderly MHD patients who underwent dialysis treatment in Blood Purification Center of Zhongda Hospital Southeast University from March to December 2022 were enrolled in this study, and were divided into LVDD group and non-LVDD group. General information, biochemical indicators and echocardiographic indexes were collected and compared between the two groups. Multivariate Logistic regression analysis was used to screen the independent risk factors for LVDD in the elderly MHD patients. Results The dialysis age and the levels of interventricular septal thickness(IVST),parathyroid hormone(PTH), and brain natriuretic peptide(BNP) in LVDD group were significantly higher than those in non-LVDD group(P<0.05). Multivariate Logistic regression analysis showed that dialysis age(OR=1.284,95%CI:1.102-1.497) and IVST(OR=83.876,95%CI:5.942-118.404) were the risk factors for LVDD in the elderly MHD patients(P<0.01). Conclusions It is important to pay attention to LVDD in the elderly MHD patients with high levels of dialysis age and IVST .

Key words: aged, maintenance hemodialysis, left ventricular diastolic dysfunction, risk factors

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