亚临床甲状腺功能减退与老年病人经皮冠状动脉介入治疗术后死亡的相关性研究

doi:10.3969/j.issn.1003-9198.2023.02.008

Abstract

Abstract: Objective To investigate the association between subclinical hypothyroidism (SCH) and death in the elderly patients with coronary artery disease (CAD) after percutaneous coronary intervention (PCI). Methods A total of 1665 elderly CAD patients aged ≥65 years old who underwent PCI were retrospectively analyzed. All patients received a follow-up for the mortality and medication after discharge for 4 years. Results The final cohort included 166 patients with SCH(9.97%) and 1499 patients (90.03%) with normal thyroid function (ET). A total of 46 patients died during the follow-up period, and the mortality rate was 2.76%. The 4-year cumulative all-cause mortality in SCH group and ET group was 12.65% and 1.67%, respectively. Kaplan-Meier analysis showed that all-cause mortality in SCH group was significantly higher than that in ET group. Cox proportional regression model analysis showed that age, hypertension, diabetes, smoking, left main coronary artery disease and SCH were the independent risk factors for death of the elderly CAD patients undergoing PCI. Conclusions SCH is an independent risk factor for the mortality of the elderly patients after PCI.

Key words: subclinical hypothyroidism, aged, death, percutaneous coronary intervention

CLC Number:

WEI Mei, GUO Qi-feng, DUAN Li-nan, YIN Ya-juan, LIU Gang, ZHENG Ming-qi, LIU Yong-sheng. Association between subclinical hypothyroidism and death in elderly patients after percutaneous coronary intervention[J]. Practical Geriatrics, 2023, 37(2): 138-141.

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Association between subclinical hypothyroidism and death in elderly patients after percutaneous coronary intervention

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