血清胱抑素C、超敏C反应蛋白预测老年心律失常心力衰竭病人预后的效能研究

doi:10.3969/j.issn.1003-9198.2022.03.015

Abstract

Abstract: Objective To investigate the effects of serum cystatin C and high-sensitivity C-reactive protein (hs-CRP) in predicting the prognosis of the elderly patients with arrhythmia and heart failure. Methods The clinical data of 96 elderly patients with arrhythmia and heart failure admitted to our hospital from December 2016 to May 2020 were collected. They were divided into death group and survival group according to the survival of the patients after 12 months of follow-up after treatment. The levels of serum cystatin C and hs-CRP were compared between the two groups, and receiver operating characteristic (ROC) curve was drawn to analyze the predictive value of cystatin C and hs-CRP for the prognosis of the elderly patients with arrhythmia and heart failure. Results All 96 patients were followed up for 12 months, and 28 patients died and 68 patients survived. The ratio of grade Ⅲ-Ⅳ of cardiac function and the levels of brain natriuretic peptide (BNP), N-terminal pro-brain natriuretic peptide (NT-proBNP), left ventricular ejection fraction (LVEF) in the death group were significantly higher than those in the survival group (all P<0.01); The levels of hs-CRP and cystatin C in the elderly patients were positively correlated with BNP, NT-proBNP and LVEF (all P<0.05). The area under the curve of serum cystatin C and hs-CRP for predicting the prognosis of the elderly patients with arrhythmia and heart failure was 0.800 (95%CI: 0.700-0.901) and 0.635 (95%CI: 0.515-0.754), respectively. Conclusions Serum cystatin C and hs-CRP have certain predictive value for the prognosis of the patients with arrhythmia and heart failure, and the sensitivity of serum cystatin C is higher.

Key words: cystatin C, high sensitivity C-reactive protein, aged, arrhythmia, heart failure

CLC Number:

R 541.6

LIU Jie-jie, SHU Liang-hui, JIANG Wei, SUI Li-jun. Effects of serum cystatin C and high-sensitivity C-reactive protein in predicting prognosis of elderly patients with arrhythmia and heart failure[J]. Practical Geriatrics, 2022, 36(3): 273-276.

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Effects of serum cystatin C and high-sensitivity C-reactive protein in predicting prognosis of elderly patients with arrhythmia and heart failure

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