老年亚临床甲状腺功能减退症与急性冠脉综合征的相关性分析

doi:10.3969/j.issn.1003-9198.2022.02.014

Abstract

Abstract: Objective To investigate the correlation between subclinical hypothyroidism(SCH) and acute coronary syndrome(ACS) in the elderly. Methods Two hundreds and forty-seven elderly patients with chest pain who were admitted to Department of Cardiology, Suqian Hospital Affiliated to Xuzhou Medical University and diagnosed with coronary heart disease (CHD) by coronary angiography(CAG) were included from January 2017 to January 2021. They were divided into ACS group and stable coronary heart disease (SCHD) group.General clinical data, the levels of serum thyroid stimulating hormone(TSH), free thyroxine(FT4), free triiodothyronine(FT3) and other biochemical parameters were collected. An age-specific serum TSH reference range was used for the diagnosis of SCH in the elderly. Multiariable Logistic regression model was applied to analyze the correlation between SCH and the severity of CHD. Results The proportion of male, hypertension, history of smoking and the incidence rate of SCH in ACS group were higher than those in SCHD group(P<0.05).The level of TSH in ACS group was higher than that in SCHD group(P<0.05).Multivariate Logistic regression analysis showed that SCH was positively correlated with ACS. Conclusions SCH is an independent risk factor for ACS in elderly patients. The level of TSH in patients with ACS is higher than that in patients with SCHD, and TSH may promote the progression of ACS.

Key words: aged, subclinical hypothyroidism, acute coronary syndromes, correlation analysis

CLC Number:

SUN Yu, WANG Yan, XU Shu-hang, LIU Chao. Correlation between subclinical hypothyroidism and acute coronary syndromes in the elderly[J]. Practical Geriatrics, 2022, 36(2): 164-167.

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Correlation between subclinical hypothyroidism and acute coronary syndromes in the elderly

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