Abstract: Objective To investigate the influencing factors of fatigue after endovascular treatment in the elderly patients with acute ischemic stroke. Methods The elderly patients (aged ≥65 years old) with acute ischemic stroke, who underwent endovascular treatment in Nanjing First Hospital, were enrolled in this study from January 2016 to February 2019. The patients were divided into fatigue group and non-fatigue group according to the score of Fatigue Severity Scale. Multivariable Logistic regression analysis was used to determine the influencing factors of fatigue after endovascular treatment in the elderly patients with acute ischemic stroke. Results A total of 371 patients were enrolled, and 169 (45.6%) patients were diagnosed as fatigue. Compared with non-fatigue group, fatigue group showed older age (P=0.001), less male (P=0.011), higher proportion of infarct site in the left cerebral hemisphere (P=0.001) and lower education level (P=0.001). Multivariate Logistic regression analysis indicated that older age, infarct site in the left cerebral hemisphere were risk factors of fatigue, and higher education level was protective factor of fatigue after endovascular treatment. Conclusions Older age and infarct site and low education level may induce the presence of fatigue after endovascular treatment in the elderly patients with acute ischemic stroke.

Key words: aged, acute ischemic stroke, fatigue, risk factor