Practical Geriatrics ›› 2021, Vol. 35 ›› Issue (5): 459-462.doi: 10.3969/j.issn.1003-9198.2021.05.007

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Correlation between heart rate variability and postoperative infection in elderly patients with hip fracture

HUANG Ze-xiao, XING Bo   

  1. Department of Emergency, the Second Affiliated Hospital of Hainan Medical University, Haikou 570311, China
  • Received:2020-06-16 Online:2021-05-20 Published:2021-05-25

Abstract: Objective To explore the correlation between heart rate variability (HRV) and postoperative infection in the elderly patients with hip fracture. Methods A total of 171 elderly patients with hip fractures admitted to our hospital for surgery from January 2018 to April 2020 were selected and divided into infection group (n=33) and non-infection group (n=138) according to whether there were infected within 7 d after operation.The differences between the two groups in basic conditions, blood biochemical indexes, and total power (TP), low frequency power (LF), very low frequency power (VLF), ratio of LF to high frequency power (LF/HF), standard deviation of R-R interval (SDNN) of HRV were compared. Multi-Logistic regression analysis was used to explore the correlation between HRV and postoperative infection in the elderly patients with hip fracture. Results The age and the proportion of diabetes mellitus in infection group were significantly higher than those in non-infection group (P<0.05). Compared with non-infection group, the levels of VLF and LF/HF in infection group were significantly lower (P<0.01). Multi-Logistic regression analysis showed that VLF (OR=0.986, 95%CI:0.976-0.997, P=0.012) and LF/HF (OR=0.416, 95%CI: 0.259-0.667, P<0.002) were independent influencing factors for postoperative infection in the elderly patients with hip fracture. The area under ROC curve (AUC) of LF/HF for predicting postoperative infection in the patients with hip fracture was significantly greater than that of VLF(0.819 vs 0.679, Z=2.227,P=0.026). The optimal cutoff value of LF/HF was 0.91,which showed a sensitivity of 60.6% and a specificity of 89.4% for the prediction of postoperative infection in the elderly patients with hip fracture. Conclusions The levels of VLF and LF/HF are closely related to postoperative infection in the elderly patients with hip fracture, and LF/HF can be a better indicator for evaluating postoperative infection in the elderly patients with hip fracture.

Key words: heart rate variability, hip fracture, postoperative infection, correlation, aged

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