Practical Geriatrics ›› 2026, Vol. 40 ›› Issue (2): 201-205.doi: 10.3969/j.issn.1003-9198.2026.02.019

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Research progress of Parkinson’s disease-related rapid eye movement sleep behavior disorder

HU Yue, TANG Xiaojia, XU Jun   

  1. Department of Neurology, Yangzhou Friendness Hospital, Yangzhou 225000, China (HU Yue);
    Department of Rehabilitation Medicine, Northern Jiangsu People’s Hospital Affiliated to Yangzhou University, Yangzhou 225001, China (TANG Xiaojia);
    China National Clinical Research Center for Neurological Diseases, Center of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China (XU Jun)
  • Received:2025-07-12 Online:2026-02-20 Published:2026-02-27
  • Contact: XU Jun, Email: neurojun@126.com

Abstract: Rapid eye movement sleep behavior disorder (RBD) is a common type of sleep disorders in Parkinson’s disease (PD) and significantly impacts patients’ quality of life. RBD has a high prevalence in the elderly population, and serves as a prodromal marker of neurodegenerative diseases. Compared with PD patients without RBD, PD-RBD patients may show more severe motor and non-motor symptoms, more severe autonomic dysfunction, faster disease progression, and worse prognosis. This article reviews recent advances in the epidemiology, clinical characteristics, pathophysiology, assessment, and management of PD-RBD. We recommend that it is necessary to establish a multidisciplinary evaluation system for PD-RBD, and strengthen the health management of RBD population, so as to identify and evaluate the disease as early as possible, delay the progression of the disease, and reduce the burden of PD.    

Key words: Parkinson’s disease, rapid eye movement sleep behavior disorder, sleep disorders, neurodegenerative diseases

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