老年T2DM病人肌少症发生与颈动脉粥样硬化的相关性研究

doi:10.3969/j.issn.1003-9198.2024.08.016

Abstract

Abstract: Objective To analyze the correlation between sarcopenia and carotid atherosclerosis in the elderly patients with type 2 diabetes mellitus(T2DM). Methods The clinical data of 97 elderly patients with T2DM admitted to our hospital from April 2021 to April 2023 were collected retrospectively. According to the skeletal muscle mass index (ASMI), the patients were divided into the sarcopenia group (41 cases) and the non-sarcopenia group (56 cases).The clinical data and carotid ultrasound indicators were collected and compared between the two groups. The risk factors affecting the occurrence of sarcopenia in the elderly patients with T2DM were analyzed. Results The levels of body mass index (BMI), T value of bone density, homextasis model assessment-insulin resitance (HOMA-IR), uric acid and ASMI in the sarcopenia group were significantly lower than those in the non-sarcopenia group (P<0.05).The number of carotid plaques, the Crouse score, semi-quantitative score, and grade score, carotid intima-media thickness (cIMT) were higher in the sarcopenia group than those in the non-sarcopenia group (P<0.05).The main grade of carotid atherosclerosis was grade 3 in the sarcopenia group, compared with grade 0 or 1 in the non-sarcopenia group, and the proportion of the two groups was significantly different (P<0.01).Logistic regression analysis showed that BMI, number of carotid plaque, cIMT, Crouse score, semi-quantitative score and grade score were risk factors for sarcopenia in the elderly patients with T2DM (P<0.05). Conclusions There is a certain correlation between sarcopenia and carotid atherosclerosis in the elderly patients with T2DM. Preventive measures should be actively taken to improve the progress of disease.

Key words: aged, type 2 diabetes, sarcopenia, carotid atherosclerosis, correlation, skeletal muscle mass index

CLC Number:

R587.1

LIANG Shanshan, LIANG Huan, YANG Shan, LIU Jianfeng. Relationship between sarcopenia and carotid atherosclerosis in elderly patients with type 2 diabetes mellitus[J]. Practical Geriatrics, 2024, 38(8): 826-830.

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Relationship between sarcopenia and carotid atherosclerosis in elderly patients with type 2 diabetes mellitus

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