红细胞体积分布宽度与老年髋部骨折病人预后的关系

doi:10.3969/j.issn.1003-9198.2024.01.007

Abstract

Abstract: Objective To investigate the relationship between red blood cell volume distribution width (RDW) and prognosis of elderly patients with hip fracture. Methods The clinical data and laboratory test results of 926 elderly patients with hip fractures admitted to our hospital from January 2014 to March 2021 were collected. The receiver operating characteristic (ROC) curve of RDW predicting the prognosis of the elderly patients with hip fractures was drawn. All patients were divided into the high RDW group and the low RDW group according to the optimal cut-off value of RDW. The basic clinical data were compared between the two groups. Survival situation was obtained from telephone follow-up, and the Kaplan-Meier survival curves of the two groups were plotted and compared. Cox proportional hazards model was used to analyze the risk factors for the prognosis of the elderly patients with hip fractures, and stratified analysis was performed for anemia and non-anemia. Results The optimal cut-off value of RDW was 14.40%. A total of 661 patients presented with low RDW (RDW≤14.40%) and 265 patients with high RDW (RDW＞14.40%). There were significant differences in age, gender, fracture type, blood transfusion, anemia, Charlson comorbidity index (CCI), time from injury to admission, hemoglobin and albumin levels between the two groups (P<0.05 or P<0.01). The median follow-up time was 43.68 months. Compared with the low RDW group, the high RDW group showed higher 30-day, 6-month and 1-year mortality rate (P<0.05 or P<0.01). Multivariate Cox regression analysis showed that RDW>14.40%, advanced age, male, CCI≥1, conservative treatment and low albumin were the independent risk factors for 1-year mortality of the elderly patients with hip fracture (all P<0.05). The stratified analysis showed a strong independent association between RDW>14.40% and 1-year risk of death in the non-anemic elderly patients with hip fracture (HR=2.969, 95%CI: 1.478-5.963, P=0.002), but there was no association in the patients with anemia (P=0.259). Conclusions RDW is closely related to the prognosis of non-anemic elderly patients with hip fracture.

Key words: red blood cell distribution width, hip fracture, aged, prognosis, anemia

CLC Number:

R 683.3

ZHANG Ming, CHEN Xi, LIU Yuehong, XIE De, WANG Zhicong, LAN Pingwen, WANG Guanglin. Relationship between red blood cell volume distribution width and prognosis of elderly patients with hip fracture[J]. Practical Geriatrics, 2024, 38(1): 22-27.

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Relationship between red blood cell volume distribution width and prognosis of elderly patients with hip fracture

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