Table of Content

20 January 2024, Volume 38 Issue 1 Previous Issue    Next Issue

Select

Effects of different tourniquet release pattern in elderly patients undergoing total knee arthroplasty LIU Yubao, WANG Zhen 2024, 38 (1):  18-21.  doi: 10.3969/j.issn.1003-9198.2024.01.006 Abstract ( 115 )   PDF (1143KB) ( 701 )   Save Objective To investigate the effects of different tourniquet release modes in the elderly patients undergoing total knee arthroplasty (TKA) and optimize the application scheme of tourniquets. Methods Ninety-three elderly patients who would undergo unilateral TKA in Department of Orthopedics, Luhe People’s Hospital of Nanjing, from 2019 to 2021 were selected, and they were randomly divided into 3 groups: Group A (receiving full duration of tourniquet application and routine release), Group B (receiving half duration of tourniquet application and routine release) and Group C (receiving half duration of tourniquet application and staged release), with 31 cases in each group. The operation time, blood loss volume, postoperative visual analogue scale (VAS) scores, knee joint range of motion (ROM) and the incidence of complications were compared among the three groups. Results There was no significant difference in operation time among the three groups (P>0.05). Compared with Group C, the intraoperative blood loss, hidden blood loss and total blood loss were lower in Group A, but higher in Group B; the postoperative drainage volume was higher in Group A and B (P<0.05). On the 1st, 7th, and 14th day after surgery, the VAS scores in Group C were lower than those in Group A and B (P<0.05); On the 7th and 14th day after surgery, the level of ROM in Group C was higher than that in Group A and B (P<0.05). There were no differences in the incidence rates of skin blisters, incision seepage, and deep vein thrombosis among the three groups, but the total incidence rate of complications in Group C was lower than that in Group A and B (P<0.05). Conclusions Compared with conventional release mode of tourniquet during TKA, half duration of tourniquet application and staged release can reduce the postoperative pain, increase the knee ROM, and promote early recovery in the elderly patients. References | Related Articles | Metrics

Select

Relationship between red blood cell volume distribution width and prognosis of elderly patients with hip fracture ZHANG Ming, CHEN Xi, LIU Yuehong, XIE De, WANG Zhicong, LAN Pingwen, WANG Guanglin 2024, 38 (1):  22-27.  doi: 10.3969/j.issn.1003-9198.2024.01.007 Abstract ( 105 )   PDF (1217KB) ( 849 )   Save Objective To investigate the relationship between red blood cell volume distribution width (RDW) and prognosis of elderly patients with hip fracture. Methods The clinical data and laboratory test results of 926 elderly patients with hip fractures admitted to our hospital from January 2014 to March 2021 were collected. The receiver operating characteristic (ROC) curve of RDW predicting the prognosis of the elderly patients with hip fractures was drawn. All patients were divided into the high RDW group and the low RDW group according to the optimal cut-off value of RDW. The basic clinical data were compared between the two groups. Survival situation was obtained from telephone follow-up, and the Kaplan-Meier survival curves of the two groups were plotted and compared. Cox proportional hazards model was used to analyze the risk factors for the prognosis of the elderly patients with hip fractures, and stratified analysis was performed for anemia and non-anemia. Results The optimal cut-off value of RDW was 14.40%. A total of 661 patients presented with low RDW (RDW≤14.40%) and 265 patients with high RDW (RDW＞14.40%). There were significant differences in age, gender, fracture type, blood transfusion, anemia, Charlson comorbidity index (CCI), time from injury to admission, hemoglobin and albumin levels between the two groups (P<0.05 or P<0.01). The median follow-up time was 43.68 months. Compared with the low RDW group, the high RDW group showed higher 30-day, 6-month and 1-year mortality rate (P<0.05 or P<0.01). Multivariate Cox regression analysis showed that RDW>14.40%, advanced age, male, CCI≥1, conservative treatment and low albumin were the independent risk factors for 1-year mortality of the elderly patients with hip fracture (all P<0.05). The stratified analysis showed a strong independent association between RDW>14.40% and 1-year risk of death in the non-anemic elderly patients with hip fracture (HR=2.969, 95%CI: 1.478-5.963, P=0.002), but there was no association in the patients with anemia (P=0.259). Conclusions RDW is closely related to the prognosis of non-anemic elderly patients with hip fracture. References | Related Articles | Metrics

Select

Establishment of a new delirium screening scale for elderly inpatients in China LIU Yadong, GAO Langli, LYU Juan, GE Ning, YUE Jirong 2024, 38 (1):  28-33.  doi: 10.3969/j.issn.1003-9198.2024.01.008 Abstract ( 95 )   PDF (1109KB) ( 753 )   Save Objective To construct a delirium screening scale for elderly inpatients in China. Methods By consulting the literature and expert group discussion, the diagnosis domain and alternative item pool were established. After the preliminary experiment, the entries were deleted according to the classical test theory (CTT) method. Combined with expert opinions and the structure of the scale, the Delirium Screen Instrument of Chinese version (DSI-CV) was established. Results A total of 730 patients were enrolled in the preliminary experiment, and the recovery rate of the scale was 100%, and the item vacancy rate was 0. Among the five dimensions of the scale, the internal consistency coefficients of acute volatility, consciousness level, attention and cognitive level were 0.748, 1.000, 0.666 and 0.853 respectively. Psychomotor changes did not participate in the internal consistency discussion due to the particularity of their two items. After CTT theory and expert group discussion, the final delirium screening scale of DSI-CV contained 14 items in 5 dimensions. Conclusions The item of DSI-CV is more in line with the cultural characteristics of China, and fully considers the daily activities of elderly hospitalized patients and their interaction with medical staff in terms of usage scenarios. References | Related Articles | Metrics

Select

Effect of virtual reality training on rehabilitation therapy in patients with mild cognitive impairment in nursing home SUN Zhicheng, WANG Ming, LI Yongyang, KONG Yimeng, ZHANG Na, DONG Yajun, GUO Ruiyu, SHI Saisai, GU Xiaomei 2024, 38 (1):  34-39.  doi: 10.3969/j.issn.1003-9198.2024.01.009 Abstract ( 117 )   PDF (1138KB) ( 1000 )   Save Objective To explore the effect of virtual reality(VR)training on the rehabilitation therapy in the patients with mild cognitive impairment(MCI)in nursing home. Methods A total of 63 patients with MCI in nursing home were randomly divided into the control group(n=31) and the VR group(n=32). Both groups received healthy education and routine care service of nursing home, and the VR group received VR training additionally.Montreal Cognitive Assessment(MoCA), Rivermead Behavioural Memory Test Second Edition (RBMT-Ⅱ), Digit Symbol Substitution Test(DSST), Animal Fluency Test (AFT), Trail Making Test (TMT) A and B, 8-foot Up and Go Test (8UGT), 30-second Arm Curl Test (30sACT) 30-second Chair Stand Test (30sCST), Back Scratch Test (BST), Chair Sit-and-Reach Test (CSRT), 2-Minute Step Test (2MST) and Quality of Life-Alzheimer’s Disease(QOL-AD) were assessed before and 6 months after intervention. Results After 6 months of intervention, the scores of MoCA, RBMT-Ⅱ, DSST, AFT, TMT-A, 8UGT, 30sACT, 30sCST, CSRT, 2MST and QOL-AD in the VR group showed significant differences compared with those before intervention and those in the control group (P<0.05 or P<0.01), while the scores of TMT-B and BST showed no significant differences (P>0.05). While all the evaluation results in the control group showed no significant differences compared with those before intervention(P>0.05). Conclusions VR training can effectively improve the cognitive function and functional fitness, and can increase the quality of life of the patients with MCI in the nursing home.It is worthy of further promotion and practice in nursing home. References | Related Articles | Metrics

Select

Comparison of intramedullary reduction technique and leverage reduction technique combined with locking plate in the treatment of complex proximal humeral fractures in elderly ZHAO Xin, YAN Junwei, YIN Zhaowei, SHI Chen, PAN Shaowei, GU Yanqing, XU Chenyang, YANG Wengbo, WANG Xiao, LIANG Bin 2024, 38 (1):  40-43.  doi: 10.3969/j.issn.1003-9198.2024.01.010 Abstract ( 96 )   PDF (1572KB) ( 670 )   Save Objective To compare the efficacy of intramedullary reduction technique and leverage reduction technique combined with locking plate in the treatment of elderly patients with complex proximal humeral fractures. Methods The patients with proximal humeral fracture treated in our hospital from September 2020 to September 2022 were selected and divided into group A (receiving leverage reduction) and group B (receiving intramedullary reduction) by random number table method, with 24 cases in each group. The operation time, fluoroscopy time, the imaging indicators, Constant-Murley score and visual analogue scale (VAS) score 3 days and 12 months after surgery, and the incidence of reduction loss 12 months after surgery were recorded and compared between the two groups. Results The operative time and fluoroscopy time in group B were shorter than those in group A (P<0.05 or P<0.01).There were no statistically significant differences in humeral head-shaft angle and humeral head height between the two groups 3 days and 12 months after surgery (P>0.05), but the loss of humeral head-shaft angle and humeral head height in group A were greater than those in group B (P<0.05). Compared with 3 days after surgery, the scores of VAS and Constant-Murley in both groups were significantly improved 12 months after surgery, and especially in group B (all P<0.05).The reduction loss rate in group B was significantly lower than that in group A (4.2% vs 33.3%, P<0.05). Conclusions Intramedullary reduction technique for the treatment of proximal humeral fractures in aged osteoporotic patients can shorten the operative time, reduce the exposure time of patients and medical staff to radiation, improve the reduction quality of humeral calcar, reduce the risk of postoperative reduction loss, and improve the postoperative shoulder joint function. References | Related Articles | Metrics

Select

Effect of Huangqi injection at Zusanli acupoint combined with pulmonary rehabilitation on antimicrobial peptide LL-37 and immune function in elderly patients with chronic obstructive pulmonary disease DENG Zaiqin, ZHOU Haibo 2024, 38 (1):  44-48.  doi: 10.3969/j.issn.1003-9198.2024.01.011 Abstract ( 95 )   PDF (1108KB) ( 797 )   Save Objective To investigate the efficacy of Huangqi injection at Zusanli acupoint combined with pulmonary rehabilitation in the elderly patients with stable chronic obstructive pulmonary disease (COPD), and to analyze the effects on serum antimicrobial peptide LL-37, inflammatory factors and T lymphocyte subsets. Methods A total of 98 elderly patients with stable COPD were divided into the Huangqi group and the control group. The control group (n=48) was given lung rehabilitation training and conventional western medicine, and the Huangqi group (n=50) received Huangqi injection at zusanli acupoint on the basis of the control group. Both groups were treated for 12 weeks. The lung function, the results of 6-minute walking test (6MWT) and dyspnea scale (mMRC), the levels of LL-37, tumor necrosis factor-α (TNF-α), interleukin 6 (IL-6) and C-reaction protein (CRP), T lymphocyte subsets count were detected and compared between the two groups before and after treatment. Results After treatment, the levels of forced vital capacity (FVC), forced expiratory volume in the first second (FEV1), the percentage of FEV1 in the predicted value (FEV1%pred), FEV1/FVC and the results of 6MWT and mMRC were significantly improved in both groups. The levels of LL-37, CD3+ T lymphocyte count, CD4+ T lymphocyte count and CD4+/CD8+ were increased, and the levels of TNF-α, IL-6 and CRP were decreased in both groups, especially in the Huangqi group (P<0.05). Conclusions Huangqi injection at Zusanli acupoint combined with pulmonary rehabilitation training can improve the lung function and exercise endurance, increase antimicrobial peptide LL-37 level and improve the immune function in the elderly patients with stable COPD. References | Related Articles | Metrics

Select

Correlation of AHNAK expression with macrophage infiltration and prognosis in patients with gastric cancer SUN Jie, ZHA Xiufang, XU Jin, ZHAO Junning, HE Wei, ZHANG Nannan 2024, 38 (1):  49-53.  doi: 10.3969/j.issn.1003-9198.2024.01.012 Abstract ( 97 )   PDF (4131KB) ( 692 )   Save Objective To investigate the expression of AHNAK in the patients with gastric cancer (GC), and to analyze the relationship between AHNAK and infiltration of immune cells, especially macrophages, and to evaluate the value of AHNAK in predicting the prognosis of GC patients. Methods The data were collected from UALCAN database.The expression of AHNAK in GC tissues and normal tissues were compared, and the expression of AHNAK was analyzed among the GC patients with different age. The relationship of AHNAK expression with the levels of immune cell infiltration and its molecular markers was analyzed by TIMER 2.0. Kaplan-Meier curve was drawn to analyze the relationship of AHNAK expression and immune cell level with overall survival (OS) of the GC patients. The influencing factors of the prognosis of GC patients were analyzed by Cox regression analysis. RMS package was used to construct the nomogram of survival probability prediction, and perform the calibration analysis and visualization of the model. Results Compared with normal tissues, the expression of AHNAK was lower in GC tissues, especially in the very old patients with GC. Kaplan-Meier survival analysis showed that the level of OS in the low AHNAK expression group was lower than that in the high AHNAK expression group (P<0.01). Immunoinfiltration analysis showed that AHNAK expression was correlated with the levels of macrophages, neutrophils, dendritic cells, B cells, CD4+ T cells and CD8+ T cell infiltration. In addition, GC patients with high level of macrophage infiltration had shorter OS (P<0.01). AHNAK expression was mainly correlated with the level of M2-type macrophage (r=0.173, P<0.001). Multivariate Cox regression analysis showed that age>65 years old, low AHNAK expression and high NM stage were the independent risk factors for poor prognosis in GC patients. The nomogram for predicting survival probability of GC patients based on N stage, M stage, age and the expression of AHNAK had a good accuracy. Conclusions The expression of AHNAK is significantly down-regulated in GC patients, especially in the very old patients. AHNAK is associated with macrophage infiltration and can be used as a biomarker to predict poor prognosis in the elderly patients with GC. References | Related Articles | Metrics

Select

Predictive value of stress hyperglycemia ratio combined with glycosylated hemoglobin on hemorrhagic transformation after intravenous thrombolysis in elderly patients with acute ischemic stroke WU Xuming, KE Xianjin, SUN Bo, SUN Zhenjie 2024, 38 (1):  54-58.  doi: 10.3969/j.issn.1003-9198.2024.01.013 Abstract ( 106 )   PDF (1329KB) ( 832 )   Save Objective To investigate the predictive value of stress hyperglycemia ratio (SHR) combined with glycosylated hemoglobin (HbA1c) on hemorrhagic transformation (HT) after intravenous thrombolysis in the elderly patients with acute ischemic stroke (AIS). Methods A total of 234 elderly AIS inpatients receiving intravenous thrombolytic therapy with recombinant tissue plasminogen activator (rt-PA) from the First People’s Hospital of Lianyungang and Affiliated Hospital of Jiangsu University from June 2018 to December 2020 were enrolled in this study. The patients were divided into HT group (n=50) and non-HT group (n=184)according to the results of computed tomography (CT) or magnetic resonance imaging (MRI) during the acute period. The clinical baseline data of the two groups were collected and compared. Multivariate Logistic regression analysis was used to analyze the risk factors for HT after rt-PA intravenous thrombolytic therapy in the elderly AIS patients. The receiver operating characteristic (ROC) curve was used to analyze the value of SHR, HbA1c and their combination in predicting HT after rt-PA intravenous thrombolytic therapy in the elderly AIS patients. Results There were statistically significant differences in age, pre-thrombolysis NIHSS score, the levels of fasting plasma glucose (FPG) and HbA1c, and the ratio of atrial fibrillation, TOAST classification and large infarct area between the two groups(P<0.05 or P<0.01). Multivariate Logistic regression analysis showed that high levels of SHR (OR=39.443, 95%CI:1.847-842.343) and HbA1c (OR=1.777, 95%CI:1.091-2.859), and large infarct area(OR=3.093, 95%CI:1.359-7.036) were the independent risk factors for HT after intravenous thrombolysis with rt-PA in the elderly AIS patients. The area under curve (AUC) of HbA1c, SHR and their combination to predict the risk of HT after intravenous thrombolysis with rt-PA in the elderly AIS patients was 0.631 (95%CI:0.541-0.721), 0.656 (95%CI:0.654-0.748) and 0.741 (95%CI:0.665-0.816), respectively. The AUC of HbA1c combined with SHR was significantly greater than that of the two indexes alone (P<0.05). Conclusions High levels of SHR and HbA1c are independent risk factors for HT after intravenous thrombolysis with rt-PA in the elderly AIS patients,and the combination of the two indexes shows significant value to predict the risk of HT after rt-PA intravenous thrombolytic therapy. References | Related Articles | Metrics

Select

Effects of high tibial osteotomy on medial compartmental knee osteoarthritis in elderly YANG Zeyu, ZOU Ling, SUN Changhui, LU Jiong, CHEN Yinan, HE Qin, HU Minwei 2024, 38 (1):  59-63.  doi: 10.3969/j.issn.1003-9198.2024.01.014 Abstract ( 85 )   PDF (1442KB) ( 476 )   Save Objective To compare the efficacy of high tibial osteotomy (HTO) in treating medial compartment knee osteoarthritis in elderly and non-elderly patients. Methods The clinical data of 26 patients who underwent HTO surgery were retrospectively analyzed. The patients were divided into elderly group (aged ≥60 years, n=18)and non-elderly group(aged <60 years, n=8). General information, surgical osteotomy angle and incidence of complications were compared between the two groups, and the scores of Visual Analogue Scale (VAS) and Knee Injury and Osteoarthritis Outcome Score (KOOS) in both groups were compared before and 1 year after surgery. Results There were no significant differences in sex, Kellgren-Lawrence (K-L) grade, body mass index (BMI), surgical osteotomy angle and incidence rates of complications between the two groups (P>0.01). There were also no significant differences in VAS and KOOS scores between the two groups before and 1 year after surgery (P>0.01), but the VAS score was significantly lower and the KOOS score was significantly higher in both groups after treatment than those before treatment (P<0.01). Conclusions HTO is safe and effective in treating medial compartment knee osteoarthritis in the elderly patients. References | Related Articles | Metrics

Select

Association of hemoglobin concentration with postoperative delirium after hip replacement in elderly patients ZHANG Jia, LIU Xinwei, LIAN Hongyu, LIU Kexin, LI Zitao 2024, 38 (1):  64-67.  doi: 10.3969/j.issn.1003-9198.2024.01.015 Abstract ( 99 )   PDF (1147KB) ( 717 )   Save Objective To investigate the risk factors of postoperative delirium in the elderly patients undergoing hip replacement and the relationship between hemoglobin (Hb) concentration and postoperative delirium. Methods The patients aged ≥65 years who underwent hip replacement in Hongqi Hospital Affiliated to Mudanjiang Medical College from June 2019 to January 2023 were enrolled in this study, and the clinical data were collected from the electronic medical record system. Postoperative delirium was assessed by Confusion Assessment Method Intensive Care Unit (CAM-ICU). Multivariate Logistic regression was used to analyze the influencing factors of postoperative delirium. Logistic regression models with different influencing factors were established, and receiver operating characteristic (ROC) curves were drawn to analyze the sensitivity of the models. Results A total of 86 patients were enrolled in the study, including 21 patients with postoperative delirium (24.4%). There were significant differences in age, postoperative Hb concentration, perioperative Hb concentration, combined with brain or lung disease, disease type and the rate of Hb concentration decline between delirium group and non-delirium group (P<0.05 or P<0.01). Multivariate Logistic regression analysis showed that age, combined with brain or lung disease, Hb concentration after surgery and Hb concentration during perioperative period were independent influencing factors for postoperative delirium in the elderly patients undergoing hip replacement. ROC curve analysis of different models showed that the combination of postoperative Hb concentration, perioperative Hb concentration change, age and combined with brain or lung disease to predict postoperative delirium in the elderly patients undergoing hip replacement had the largest area under the curve. Conclusions In the perioperative period of elderly patients undergoing hip replacement, correcting low Hb concentration after surgery and avoiding great change of Hb concentration during perioperative period are important to reduce the occurrence of postoperative delirium. References | Related Articles | Metrics

Select

Analysis of characteristics and influencing factors of fall injury in hospitalized elderly patients ZHU Jiao, XIA Lili, XU Minzheng, LIU Ying, WANG Yingxin, YOU Zhengyuan 2024, 38 (1):  81-85.  doi: 10.3969/j.issn.1003-9198.2024.01.019 Abstract ( 95 )   PDF (1108KB) ( 1034 )   Save Objective To investigate the distribution characteristics of injury degree caused by falls in the elderly inpatients, and to analyze the influencing factors. Methods The clinical data of 382 inpatients aged ≥60 years old who had fallen in the First Affiliated Hospital of Nanjing Medical University from 2017 to 2021 were retrospectively collected. According to the degree of injury caused by falls, they were divided into no injury group, first-level injury group, second-level injury group and third-level injury group. Fasting biochemical factors, coagulation indexes and blood routine test results of the latest morning within 7 days before falls were collected and compared among the groups. The correlation between different indicators was represented by Spearman correlation coefficient. The risk factors of injury caused by falls in the elderly inpatients were analyzed by binary Logistic regression analysis. Results Among the 382 elderly inpatients, the main injury degree was first-level injury (n=150, 39.27%), followed by no injury (n=145, 37.96%), third-level injury (n=52, 13.61%) and second-level injury (n=35, 9.16%). Univariate analysis showed that there were significant differences in age, prothrombin time (PT), international standard ratio (INR), activated partial thrombin time (APTT), fibrinogen (FIB) among the elderly patients with different degrees of injury caused by falls (P＜0.05 or P＜0.01). Spearman correlation analysis showed that the degree of injury caused by falls in the hospitalized elderly patients was positively correlated with age, PT, INR, APTT and FIB (r=0.188, 0.169, 0.177, 0.147, 0.131, all P<0.05). Logistic regression analysis showed that age (OR=1.035) and FIB (OR=1.330) were the independent influencing factors of injury caused by falls. Conclusions The degree of injury caused by falls is associated with age and coagulation function in the elderly inpatients, and the population with high risk of injury should receive hierarchical management. References | Related Articles | Metrics

Select

Effect of ambulation training combined with Buerger movement on improving postprandial hypotension after breakfast in elderly inpatients with hypertension LI Jinluan, DU Jun 2024, 38 (1):  86-89.  doi: 10.3969/j.issn.1003-9198.2024.01.020 Abstract ( 90 )   PDF (1090KB) ( 562 )   Save Objective To observe the effect of ambulation training combined with Buerger movement on improving postprandial hypotension (PPH) after breakfast in the elderly inpatients with hypertension. Methods The elderly hypertensive patients hospitalized in Department of Cardiovascular Internal Medicine of Nanjing Chest Hospital were selected as the research subjects. The Plan-Do-Check-Action (PDCA) management method was used to analyze the reasons for the high incidence rate of PPH after breakfast in 33 patients (control group) who were hospitalized from November 15, 2021 to April 17, 2022, and 38 patients (observation group) who were hospitalized from May 5 to October 31, 2022 received ambulation training combined with Buerger movement after breakfast. The incidence rate of PPH 30, 60, 90, and 120 min after breakfast, the awareness of PPH knowledge, and the proportion of active exercise after breakfast were compared between the two groups. The awareness of PPH knowledge and implementation rate of propaganda and education among the nurses before and after project implementation were compared. Results There were no significant differences in gender, age and systolic blood pressure (SBP) between the two groups (P>0.05). The incidence rate of PPH after breakfast in the observation group was significantly lower than that in the control group (15.79% vs 45.45%, P=0.006). The awareness rates of PPH concept, susceptible population and occurrence time, and the proportion of active exercise after breakfast in the observation group were significantly higher than those in the control group (all P<0.01). After the implementation of the project, the awareness rates of PPH concept, characteristics, occurrence time and non-drug prevention measures, and the implementation rate of PPH propaganda and education among the nurses were significantly improved (P<0.05 or P<0.01). Conclusions Ambulation training combined with Buerger movement can effectively reduce the occurrence of PPH after breakfast in the elderly inpatients with hypertension, and the PDCA program can improve the awareness rate of PPH knowledge among the patients and nurses, conduce to the early identification and intervention, and minimize the harm of PPH. References | Related Articles | Metrics

Select

Effectiveness of Kihon Checklist in assessing frailty in hospitalized elderly patients CHEN Wenxiu, JIANG Qian, LI Qi, WANG Luyao, WU Jingyi, WU Zhao, LAI Xiaoxing, LIU Wei 2024, 38 (1):  90-93.  doi: 10.3969/j.issn.1003-9198.2024.01.021 Abstract ( 98 )   PDF (1096KB) ( 908 )   Save Objective To explore the clinical application value of Kihon Checklist in hospitalized elderly patients. Methods Three hundred elderly patients hospitalized in Peking Union Medical College Hospital from September 2021 to May 2022 were selected as the study subjects by convenient sampling method. All the patients completed comprehensive geriatric assessment within 3 days after admission, and were assessed with Fried frailty phenotype and Kihon Checklist respectively. Results The average age of the 300 elderly was 77.97±9.08 years old. A total of 122 patients with frailty (40.67%) were screened using Fried frailty phenotype, and 144 patients with frailty (48.00%) were screened using Kihon Checklist. The Kappa value of the consistency test between Fried frailty phenotype and Kihon Checklist was 0.745 (P<0.01). Spearman correlation analysis showed that the score of Kihon Checklist was negatively correlated with the scores of Mini-Mental State Examination (MMSE), Short Form Mini-Nutrition Assessment (MNA-SF), Barther index and Lawton Brody index (r=-0.449, -0.542, -0.444, -0.730, all P<0.01), and positively correlated with Charlson complication index (r=0.353, P<0.01). Receiver operating characteristic curve showed that the area under the curve for assessing frailty in elderly hospitalized patients using Kihon Checklist was 0.960, with a sensitivity of 0.831 and a specificity of 0.934, and the cut-off value was 9 points. Conclusions Kihon Checklist is fast, simple, and sensitive in screening frailty in hospitalized elderly patients, and it can guide medical staff to provide corresponding support to elderly patients with frailty. References | Related Articles | Metrics