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Practical Geriatrics    2023, 37 (10): 1076-1080.   DOI: 10.3969/j.issn.1003-9198.2023.10.026 Abstract （141）      PDF （999KB）（6364）       Reference | Related Articles | Metrics

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Practical Geriatrics    2023, 37 (9): 878-881.   DOI: 10.3969/j.issn.1003-9198.2023.09.004 Abstract （113）      PDF （1042KB）（4906）       Reference | Related Articles | Metrics

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Practical Geriatrics    2023, 37 (10): 978-983.   DOI: 10.3969/j.issn.1003-9198.2023.10.002 Abstract （118）      PDF （1157KB）（4764）       Reference | Related Articles | Metrics

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Effects of cognitive emotion regulation strategies on frailty in elderly patients with comorbidities MIAO Yu-fei, QIAN Xiang-yun Practical Geriatrics    2023, 37 (8): 839-842.   DOI: 10.3969/j.issn.1003-9198.2023.08.020 Abstract （134）      PDF （1063KB）（4531）       Objective To explore the cognitive emotion regulation strategies adopted by the elderly patients with comorbidities in response to events and its relationship with frailty. Methods From May to December 2021, the convenience sampling method was used to select 300 elderly patients with comorbidities in Nantong Third People's Hospital as the research subjects. Questionnaires conducted using the patient general information questionnaire,Chinese version of Tilburg Frailty Assessment Scale, and Chinese version of Cognitive Emotion Regulation Questionnaire(CERQ-C). The incidence rate of frailty and the relationship of cognitive emotion regulation strategy with frailty were analyzed. Results The incidence rate of frailty in the elderly patients with comorbidities was 57.0%(171/300). There were significant differences in age, residence status, marital status, recent memory, smoking, drinking and cognitive emotional regulation between the frailty group and the non-frailty group. Binary Logistic regression analysis showed that aged, recent memory decline and non-adaptive cognitive emotional regulation were risk factors for frailty, while adaptive cognitive emotion regulation, refocus planning and drinking were protective factors. Conclusions The prevelence of frailty in elderly patients with comorbidities is high. Elderly patients with comorbidities tend to adopt non-adaptive cognitive emotion regulation strategies in response to negative life events. Cognitive emotional regulation strategies, age, recent memory and drinking can affect frailty. Reference | Related Articles | Metrics

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Practical Geriatrics    2024, 38 (2): 109-113.   DOI: 10.3969/j.issn.1003-9198.2024.02.001 Abstract （173）      PDF （1278KB）（3698）       Reference | Related Articles | Metrics

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Practical Geriatrics    2024, 38 (2): 119-122.   DOI: 10.3969/j.issn.1003-9198.2024.02.003 Abstract （155）      PDF （1125KB）（2633）       Reference | Related Articles | Metrics

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Practical Geriatrics    2024, 38 (3): 232-235.   DOI: 10.3969/j.issn.1003-9198.2024.03.005 Abstract （113）      PDF （1157KB）（2562）       Reference | Related Articles | Metrics

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Study on the predictive value of Padua score for venous thromboembolism in elderly inpatients GAO Wei-fei, LI Peng, QIAO Zhen, MA Li-na Practical Geriatrics    2023, 37 (8): 803-805.   DOI: 10.3969/j.issn.1003-9198.2023.08.012 Abstract （115）      PDF （1045KB）（2543）       Objective To assess the predictive value of Padua score for venous thromboembolism(VTE) in the elderly inpatients. Methods A retrospective analysis was performed and 150 elderly inpatients in Department of General Practice of Hangzhou Third People's Hospital from January 2018 to June 2021 were included. All of them underwent CT pulmonary angiography or venous ultrasound of both upper(lower)limbs, and were divided into VTE group and non-VTE group. The baseline data including age, gender, underlying disease, Padua score, D-dimer, mean platelet volume(MPV), albumin were collected and compared between the two groups. Multivariate Logistic regression was used to analyze the risk factors of VTE. Receiver operating characteristic (ROC) curve analysis was carried out to assess the predictive value of Padua score. Results There were statistically significant differences in Padua score, age, hypertension, acute infection, D-dimer, MPV and albumin between the two groups. Multivariate Logistic regression analysis showed that aged ≥85 years old was the independent risk factor for VTE of elderly inpatients. The area under the curve (AUC) of Padua score to predict the incidence of VTE was 0.631, with a cut-off value of 4.5, and the Youden index was 0.36. Conclusions The predictive value of Padua score for VTE in elderly inpatients is limited. Reference | Related Articles | Metrics

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Practical Geriatrics    2023, 37 (10): 1041-1043.   DOI: 10.3969/j.issn.1003-9198.2023.10.016 Abstract （93）      PDF （1199KB）（2385）       Reference | Related Articles | Metrics

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Practical Geriatrics    2024, 38 (3): 299-303.   DOI: 10.3969/j.issn.1003-9198.2024.03.021 Abstract （90）      PDF （1073KB）（2366）       Reference | Related Articles | Metrics

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Practical Geriatrics    2024, 38 (2): 193-197.   DOI: 10.3969/j.issn.1003-9198.2024.02.021 Abstract （110）      PDF （1061KB）（2322）       Reference | Related Articles | Metrics

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Practical Geriatrics    2023, 37 (9): 873-877.   DOI: 10.3969/j.issn.1003-9198.2023.09.003 Abstract （149）      PDF （1107KB）（2228）       Reference | Related Articles | Metrics

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Practical Geriatrics    2023, 37 (9): 882-885.   DOI: 10.3969/j.issn.1003-9198.2023.09.005 Abstract （122）      PDF （1059KB）（2046）       Reference | Related Articles | Metrics

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Practical Geriatrics    2024, 38 (3): 223-227.   DOI: 10.3969/j.issn.1003-9198.2024.03.003 Abstract （123）      PDF （1187KB）（2004）       Reference | Related Articles | Metrics

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Practical Geriatrics    2023, 37 (9): 956-959.   DOI: 10.3969/j.issn.1003-9198.2023.09.022 Abstract （69）      PDF （1030KB）（1939）       Reference | Related Articles | Metrics

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Practical Geriatrics    2023, 37 (9): 886-889.   DOI: 10.3969/j.issn.1003-9198.2023.09.006 Abstract （108）      PDF （1076KB）（1868）       Reference | Related Articles | Metrics

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Practical Geriatrics    2023, 37 (10): 984-988.   DOI: 10.3969/j.issn.1003-9198.2023.10.003 Abstract （101）      PDF （1204KB）（1809）       Reference | Related Articles | Metrics

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Practical Geriatrics    2023, 37 (10): 1056-1058.   DOI: 10.3969/j.issn.1003-9198.2023.10.021 Abstract （85）      PDF （971KB）（1748）       Reference | Related Articles | Metrics

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Practical Geriatrics    2023, 37 (10): 973-977.   DOI: 10.3969/j.issn.1003-9198.2023.10.001 Abstract （204）      PDF （1201KB）（1721）       Reference | Related Articles | Metrics

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Practical Geriatrics    2023, 37 (9): 869-872.   DOI: 10.3969/j.issn.1003-9198.2023.09.002 Abstract （179）      PDF （1159KB）（1663）       Reference | Related Articles | Metrics

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Practical Geriatrics    2023, 37 (7): 728-731.   DOI: 10.3969/j.issn.1003-9198.2023.07.019 Abstract （100）      PDF （1022KB）（1659）       Reference | Related Articles | Metrics

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Practical Geriatrics    2023, 37 (9): 865-868.   DOI: 10.3969/j.issn.1003-9198.2023.09.001 Abstract （142）      PDF （1064KB）（1588）       Reference | Related Articles | Metrics

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Practical Geriatrics    2024, 38 (3): 228-231.   DOI: 10.3969/j.issn.1003-9198.2024.03.004 Abstract （100）      PDF （1176KB）（1546）       Reference | Related Articles | Metrics

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Effect of high flux hemodialysis and hemodiafiltration on the quality of life in elderly patients receiving maintenance hemodialysis XIE Qing-lei, ZHANG Liu-ping, WANG Yue Practical Geriatrics    2023, 37 (7): 719-722.   DOI: 10.3969/j.issn.1003-9198.2023.07.017 Abstract （79）      PDF （1048KB）（1482）       Objective To investigate the effects of hemodiafiltration (HDF) and high flux hemodialysis ( HFHD) on the quality of life(QOL) in the elderly patients receiving maintenance hemodialysis(MHD). Methods A cross-sectional study was conducted in Blood Purification Center, Zhongda Hospital, Southeast University from January 2019 to December 2021, and the clinical data of all patients were collected. Kidney disease quality of life-short form (KDQOL-SF) was applied to assess the health-related quality of life (HRQL) of the patients. The efficacy and QOL were compared between the patients receiving HFHD and those receiving HDF after propensity score matching(PSM). Results There were significant differences in scores of burden of kidney disease in kidney disease-targeted areas (KDTA) and scores of physical functioning, general health, and vitality of 36-item health survey (SF-36) (P<0.05). Conclusions In elderly MHD patients, disease burden caused by HDF is heavier than HFHD, but HDF can improve QOL -related physiological functions, general health and vitality. Reference | Related Articles | Metrics

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Practical Geriatrics    2023, 37 (8): 761-764.   DOI: 10.3969/j.issn.1003-9198.2023.08.002 Abstract （102）      PDF （1088KB）（1446）       Reference | Related Articles | Metrics

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Practical Geriatrics    2023, 37 (7): 741-745.   DOI: 10.3969/j.issn.1003-9198.2023.07.022 Abstract （93）      PDF （1058KB）（1438）       Reference | Related Articles | Metrics

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Predictive value of systemic immune-inflammatory index for lower extremity deep venous thrombosis in elderly patients with heart failure with reduced ejection fraction YANG Shao-qi, YANG Yang, DENG Li-na, ZHAI Zhi-xin Practical Geriatrics    2023, 37 (7): 695-699.   DOI: 10.3969/j.issn.1003-9198.2023.07.012 Abstract （113）      PDF （1116KB）（1435）       Objective To evaluate the predictive value of systemic immune-inflammation index (SII) for lower extremity deep venous thrombosis (LEDVT) in the elderly patients with heart failure with reduced ejection fraction (HFrEF). Methods A retrospective study was performed, and a total of 163 elderly HFrEF patients in our hospital from August 2020 to May 2022 were enrolled in this study. The independent risk factors of LEDVT were screened by univariate and multivariate Logistic regression analysis, and the predictive value of the variants for the incidence of LEDVT was evaluated by receiver operating characteristic (ROC) curve. Results Thirty-two cases (19.6%) presented with LEDVT. Compared to the non-LEDVT group, the age, the levels of Autar score, SII and plasma D-dimer at admission were significantly higher in the LEDVT group (P<0.05). Multivariate Logistic regression showed that the level of SII, plasma D-dimer were independent influencing factors of LEDVT. ROC curve showed that SII had significant predictive value for LEDVT with an AUC of 0.782, and the cutoff value of SII was 629×109/L. Kaplan-Meier survival curve analysis showed that the incidence rate of LEDVT in high SII group (>629×109/L) was significantly higher than that in low SII group (χ2=9.133, P=0.003). Conclusions SII level at admission can be used as an independent risk predictor of LEDVT in the elderly patients with HFrEF. Reference | Related Articles | Metrics

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Research progress of calprotectin S100A8/S100A9 in Alzheimer's disease WU Jinli, YANG Xiaojuan Practical Geriatrics    2025, 39 (2): 197-201.   DOI: 10.3969/j.issn.1003-9198.2025.02.020 Abstract （48）      PDF （1039KB）（1399）       Alzheimer's disease(AD) is characterized by progressive memory loss. Based on the emerging theory of microbe-gut-brain axis, the changes in intestinal flora might activate the intestinal inflammation. Calprotectin, as a marker of intestinal inflammation, is a key substance in the brain-gut axis of AD. Its subunits S100A8 and S100A9 are also closely related to the Aβ theory and neuroinflammation theory in AD, respectively. Therefore, this article reviews the main functions of S100A8/S100A9 protein and its new research progress in AD-related pathogenesis, risk factors, prevention and treatment, in order to provide new research directions for the treatment of AD. Reference | Related Articles | Metrics

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Analysis of the current situation and influencing factors of demoralization syndrome in elderly patients with chronic heart failure GAO Wenjun, SUN Qing, LIU Mengtan, ZHOU Dan Practical Geriatrics    2024, 38 (11): 1105-1109.   DOI: 10.3969/j.issn.1003-9198.2024.11.006 Abstract （72）      PDF （1106KB）（1384）       Objective To investigate the current situation of demoralization syndrome in the elderly patients with chronic heart failure (CHF) and to analyze the influencing factors. Methods Convenience sampling method was used to enroll the elderly patients with CHF admitted to Changhai Hospital from June 2022 to June 2023 in this study. The patients were surveyed using a general information questionnaire, Chinese version of the Demoralization Scale-Ⅱ, Heart Failure Somatic Perception Scale (HFSPS), Fear of Progression Questionnaire-Short Form (FoP-Q-SF), International Physical Activity Questionnaire (IPAQ) and Perceived Social Support Scale (PSSS). Multiple linear regression was used to analyze the influencing factors of demoralization syndrome. Results The score of Demoralization Scale-Ⅱ in 245 elderly patients with CHF was 16.55±4.76, which was at a medium level. Pearson correlation analysis showed that demoralization syndrome was positively correlated with body perception, fear of disease progression and sedentary behavior (r=0.475, 0.440, 0.499, respectively), and negatively correlated with social support (r=-0.491). Multiple linear regression analysis showed that per capita monthly household income, disease duration, physical perception, fear of disease progression, sedentary behavior, and social support were independent influencing factors (P<0.05) for demoralization syndrome in the elderly patients with CHF, and could jointly explain 45.9% of the variation in demoralization syndrome. Conclusions The level of demoralization syndrome in the elderly patients with CHF is at a medium level. Low income, long course of disease, strong physical perception, high fear of disease progression and sedentary lifestyle were risk factors for the demoralization syndrome of patients with CHF, while social support is a protective factor. Reference | Related Articles | Metrics

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Epidemiological characteristics of metabolic syndrome in the elderly aged 60 years and above in Nanjing, China DENG Tian-rui, YAO Zhu-ling, WANG Zhi-yong, YE Qing, TANG Wei, XU Fei Practical Geriatrics    2023, 37 (8): 819-822.   DOI: 10.3969/j.issn.1003-9198.2023.08.016 Abstract （111）      PDF （1055KB）（1380）       Objective To investigate the characteristics of metabolic syndrome(MS) in the elderly population aged 60 and over in Nanjing, and to investigate the influencing factors of MS. Methods From April to October 2017, a total of 15 545 residents aged ≥60 years were selected in Nanjing by multi-stage stratified cluster sampling method. The prevalence characteristics of MS was descriptively analyzed, and the influencing factors of MS were analyzed by Logistic regression model. Results The prevalence of MS in the elderly aged ≥60 years was 28.3%(95%CI: 27.6%-29.0%) in Nanjing. The prevalence was higher in those aged 70-79 years than that in those aged 60-69 years and ≥80 years, being higher in urban areas than that in suburban areas, being higher in those with insufficient physical activity than that in those with adequate physical activity, being higher in those with family history of hypertension or diabetes than that in those without. Among the five components of MS, hypertension had the highest prevalence(60.8%), followed by central obesity(39.1%), hypertriglyceridemia(33.9%), hyperglycemia(33.3%) and low high-density lipoproteinemia(14.7%). Logistic regression analysis showed that aged 70-79 years, family history of hypertension and diabetes were the risk factors for MS, while living in suburban area and sufficient physical activity were the protective factors. Conclusions The prevalence of MS in the elderly population in Nanjing is high. Tailored interventions are encouraged for people aged 70-79 years or those with family history of hypertension and diabetes. Reference | Related Articles | Metrics