青藤碱治疗糖尿病肾病的研究进展

doi:10.3969/j.issn.1003-9198.2025.11.019

Abstract

Abstract: Diabetic kidney disease, a common complication of diabetes mellitus, is characterized by a complex pathogenesis involving the interplay of multiple factors, including hyperglycemia, oxidative stress, inflammatory responses, and metabolic disorders. In recent years, sinomenine, a traditional Chinese herbal component, has demonstrated significant potential in the treatment of various renal diseases due to its pharmacological properties of anti-inflammation, antioxidant effects, and immune regulation. This article reviews the pathogenesis of diabetic kidney disease and the specific mechanisms by which sinomenine treats diabetic kidney disease through its anti-inflammatory and antioxidant effects. Additionally, it preliminarily explores the prospects of integrating the multi-target intervention characteristics of sinomenine with the holistic treatment philosophy of traditional Chinese medicine, aiming to provide a dialectical approach for the comprehensive management of diabetic kidney disease.

Key words: sinomenine, diabetic kidney disease, inflammatory response, oxidative stress

CLC Number:

R 587.2

LIU Miao, MIN Danyan, CHU Wenwen, QIAO Cheng, ZHAN Qiunan, ZHAO Junli. Research progress of the effects of sinomenine in the treatment of diabetic kidney disease[J]. Practical Geriatrics, 2025, 39(11): 1169-1173.

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Research progress of the effects of sinomenine in the treatment of diabetic kidney disease

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