[1] WATANABE Y,OKADA K,KONDO M,et al. Oral health for achieving longevity[J].Geriatr Gerontol Int,2020,20(6):526-538. [2] GREENLAND J C, WILLIAMS-GRAY C H, BARKER R A. The clinical heterogeneity of Parkinson’s disease and its therapeutic implications[J]. Eur J Neurosci, 2019, 49(3):328-338. [3] SUZUKI H, FURUYA J, HIDAKA R, et al. Patients with mild cognitive impairment diagnosed at dementia clinic display decreased maximum occlusal force: a cross-sectional study[J]. BMC Oral Health, 2021,21(1):665. [4] SAWADA N, TAKEUCHI N, EKUNI D, et al. Oral function, nutritional status and physical status in Japanese independent older adults[J]. Gerodontology, 2022, 39(4):359-365. [5] 屠杭佳,张书怡,方雨慧,等.社区老年人口腔衰弱现状及影响因素分析[J].中华护理杂志,2023, 58(11): 1351-1356. [6] MATSUBARA C, SHIROBE M, FURUYA J, et al. Effect of oral health intervention on cognitive decline in community-dwelling older adults: a randomized controlled trial[J]. Arch Gerontol Geriatr,2021,92:1-11. [7] TANAKA T, TAKAHASHI K, HIRANO H, et al. Oral frailty as a risk factor for physical frailty and mortality in community-dwelling elderly[J]. J Gerontol A Biol Sci Med Sci, 2018,73(12):1661-1667. [8] 刘星,张雪梅.老年人口腔衰弱的研究进展[J].现代临床护理,2022,21(1):72-77. [9] TAKEUCHI N, SAWADA N, EKUNI D,etal. Oral diadochokinesis is related to decline in swallowing function among community-dwelling Japanese elderly:a cross-sectional study[J]. Aging Clin Exp Res,2021,33(2):399-405. [10] HE F, LUO H, YIN L, et al. Poor oral health as a risk factor for dementia in a Swedish population: a cohort study with 40 years of follow-up[J]. J Alzheimers Dis,2023,92(1):171-181. [11] YAMAGUCHI S, MURAKAMI T, SATOH M, et al. Associations of dental health with the progression of hippocampal atrophy in community-dwelling individuals: the Ohasama Study[J]. Neurology, 2023,101(10):e1056-e1068. [12] CERUTTI-KOPPLIN D, FEINE J, PADILHA DM, et al. Tooth loss increases the risk of diminished cognitive function: a systematic review and Meta-analysis[J]. JDR Clin Trans Res, 2016,1(1):10-19. [13] STAEHR C, GIBLIN J T, GUTIÉRREZ-JIMÉNEZ E, et al. Neurovascular uncoupling is linked to microcirculatory dysfunction in regions outside the ischemic core following ischemic stroke[J]. J Am Heart Assoc, 2023,12(11):e029527. [14] CHEN X, YAO N, LIN Z,et al. Inhibition of the immunoproteasome subunit LMP7 ameliorates cerebral white matter demyelination possibly via TGFβ/Smad signaling[J]. Evid Based Complement Alternat Med,2021,2021:6426225. [15] SONG G, PENG G, ZHANG J, et al. Uncovering the potential role of oxidative stress in the development of periodontitis and establishing a stable diagnostic model via combining single-cell and machine learning analysis[J]. Front Immunol, 2023,14:1181467. [16] PANG Q, WU Q, HU X, et al. Tooth loss, cognitive impairment and chronic cerebral ischemia[J]. J Dent Sci, 2020,15(1):84-91. [17] FURUKAWA M, TADA H, WANG J, et al. Molar loss induces hypothalamic and hippocampal astrogliosis in aged mice[J]. Sci Rep, 2022,12(1):6409. [18] TERREROS-RONCAL J, MORENO-JIMÉNEZ E P, FLOR-GARCÍA M, et al. Impact of neurodegenerative diseases on human adult hippocampal neurogenesis[J]. Science, 2021,374(6571):1106-1113. [19] HE Y, ZHU J, HUANG F, et al. Age-dependent loss of cholinergic neurons in learning and memory-related brain regions and impaired learning in SAMP8 mice with trigeminal nerve damage[J]. Neural Regen Res, 2014,9(22):1985-1994. [20] HU J, WANG X, KONG W, et al. Tooth loss suppresses hippocampal neurogenesis and leads to cognitive dysfunction in juvenile Sprague-Dawley rats[J]. Front Neurosci, 2022,16:839622. [21] 江青松,胡江琪,路云萍,等.牙齿缺失与认知障碍相关性研究现状与展望[J].口腔颌面修复学杂志,2023,24(2):81-86. [22] PANZA F, LOZUPONE M, LOGROSCINO G,et al. A critical appraisal of amyloid-β-targeting therapies for Alzheimer disease[J]. Nat Rev Neurol, 2019,15(2):73-88. [23] BORGNAKKE W S, GENCO R J, EKE P I, et al. Diabetes in America[M]. 3rd ed. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases (US), 2018, CHAPTER 31. [24] 李晶卉,连腾宏,郭鹏,等.牙周炎与阿尔茨海默病[J].中国神经免疫学和神经病学杂志,2022,29(4):321-324. [25] KANAGASINGAM S, VON RUHLAND C, WELBURY R, et al. Antimicrobial, polarizing light, and paired helical filament properties of fragmented tau peptides of selected putative gingipains[J]. J Alzheimers Dis, 2022,89 (4): 1279-1291. [26] WU Q, LI Z, ZHANG Y, et al. Cyclic di-AMP Rescues porphyromonas gingivalis-aggravated atherosclerosis[J]. J Dent Res,2023,102(7):785-794. [27] OWOYELE PV, MALEKZADEH S. Porphyromonas gingivalis, neuroinflammation and Alzheimer’s disease[J]. Niger J Physiol Sci, 2022,37(2):157-164. [28] ZHANG Y, SUN Y, HU Y, et al. Porphyromonas gingivalis msRNA P.G_45033 induces amyloid-β production by enhancing glycolysis and histone lactylation in macrophages[J]. Int Immunopharmacol, 2023,121:110468. [29] HAN J H, LEE H J, HAN J W, et al. Loss of functional dentition is associated with cognitive impairment[J]. J Alzheimers Dis, 2020,73(4):1313-1320. [30] MATSUBARA C, SHIROBE M, FURUYA J, et al. Effect of oral health intervention on cognitive decline in community-dwelling older adults: a randomized controlled trial[J]. Arch Gerontol Geriatr,2021,92:1-11. [31] ZHANG D, RUAN J, PENG S,et al. Synaptic-like transmission between neural axons and arteriolar smooth muscle cells drives cerebral neurovascular coupling[J]. Nat Neurosci, 2024,27(2):232-248. [32] DIOLI C, PAPADIMITRIOU G, MEGALOKONOMOU A, et al. Chronic stress, depression, and Alzheimer’s disease: the triangle of oblivion[J]. Adv Exp Med Biol, 2023,1423:303-315. [33] LIN C S, LIN H H, FANN S W, et al. Association between tooth loss and gray matter volume in cognitive impairment[J]. Brain Imaging Behav, 2020,14(2):396-407. [34] NAKAMURA T, ZOU K, SHIBUYA Y, et al. Oral dysfunctions and cognitive impairment/dementia[J]. J Neurosci Res,2021,99(2):518-528. [35] SUN W, OKIHARA H, OGAWA T, et al. Pre-adolescent diet normalization restores cognitive function in young mice[J]. J Clin Med,2023,12(11):3642. [36] NAGATANI M, TANAKA T, SON B K, et al. Oral frailty as a risk factor for mild cognitive impairment in community-dwelling older adults: Kashiwa study[J]. Exp Gerontol, 2023,172:112075. [37] PATRIAT R, PISHARADY P K, AMUNDSEN-HUFFMASTER S, et al. White matter microstructure in Parkinson’s disease with and without elevated rapid eye movement sleep muscle tone[J]. Brain Commun,2022,4(2):fcac027. |