Abstract: Objective To investigate the status of nutrition and its relationship with major adverse cardiovascular events (MACEs) in the elderly patients with acute ST-segment elevation myocardial infarction (STEMI) who underwent percutaneous coronary intervention (PCI). Methods A total of 361 elderly patients with STEMI who underwent emergency PCI from 2018 to 2021 were consecutively enrolled. Nutritional Risk Screening 2002 (NRS-2002) was used to evaluate the risk of malnutrition (NRS-2002 ≥3 was defined as being at risk of malnutritional). The main study endpoint was the occurrence of MACEs within one year of follow-up,including all-cause death, recurrent myocardial infarction, stent thrombosis, and unplanned repeat revascularization. Cox regression analysis was used to investigate the influencing factors of MACEs. Results Among 361 patients, 108 patients (29.92%) had an NRS-2002 score of ≥3. After one year of follow-up, 21 cases (5.82%) were lost to follow-up, and a total of 66 patients presented with MACEs (66/340, 19.41%). The elderly STEMI patients with NRS-2002≥3 were more prone to MACEs than those with NRS-2002<3 (P<0.001). Multivariate Cox proportional hazards analysis showed that NRS-2002≥3 is an independent risk factor for MACEs in the elderly STEMI patients who underwent PCI (OR=2.868, 95%CI: 1.395-5.897, P=0.004). Conclusions The elderly patients with STEMI should pay attention to malnutrition.NRS-2002≥3 is an independent risk factor for poor prognosis in the elderly STEMI patients who underwent PCI.

Key words: ST-segment elevation myocardial infarction, Nutritional Risk Screening-2002, aged, prognosis, percutaneous coronary intervention