Practical Geriatrics ›› 2025, Vol. 39 ›› Issue (5): 444-449.doi: 10.3969/j.issn.1003-9198.2025.05.003

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Advances in energy and protein treatment goals for elderly critically ill patients

JIANG Jie, ZHOU Dandan, ZHU Baohua   

  1. Department of ICU, Nanjing Central Hospital, Nanjing 210008, China (JIANG Jie, ZHU Baohua); Department of ICU, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210028, China (ZHOU Dandan)
  • Received:2025-03-24 Online:2025-05-20 Published:2025-05-20
  • Contact: ZHU Baohua, Email: 13512538600@139.com

Abstract: With the increasing aging population, the number of elderly critically ill patients is rising, making nutritional support issues urgent. This review provides an in-depth analysis of the metabolic characteristics of energy and protein metabolism in the elderly critically ill patients, explores the establishment of clinical nutritional goals, and emphasizes the importance of individualized nutritional therapy. Research has demonstrated significant heterogeneity in energy metabolism among the elderly critically ill patients, along with the phenomenon of “anabolic resistance” in protein metabolism, highlighting the need for optimization of traditional nutritional support strategies. Based on recent studies and clinical guidelines, this review emphasizes that energy and protein intake should be precisely adjusted according to the patient’s condition. In the future, individualized, precision-based, phased, and multidisciplinary collaborative nutritional treatment strategies will become the mainstream approach, promising better clinical outcomes for the elderly critically ill patients and reducing the burden on public healthcare systems.

Key words: aged, critically illness, energy metabolism, protein metabolism, nutritional support

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