肌少症对老年结直肠癌病人术后切口愈合的影响

doi:10.3969/j.issn.1003-9198.2025.08.009

摘要/Abstract

摘要： 目的探讨肌少症对老年结直肠癌病人术后切口愈合的影响。方法收集2020年6月至2024年4月在江苏盛泽医院普外科接受根治性结直肠癌切除手术的104例病人的临床资料。根据术后切口愈合情况将其分为切口愈合延迟组(n=24)和切口愈合良好组(n=80),比较2组间术前一般临床资料、术中及术后临床指标,采用多因素logistic回归分析术后切口愈合的影响因素。结果与切口愈合良好组比较,切口愈合延迟组肌少症比例、年龄、糖尿病比例、术中出血量、术后并发症发生率差异有统计学意义。多因素logistic回归分析显示,肌少症(OR=3.559,95%CI:1.203~10.53,P=0.022)、术中出血量(OR=3.383,95%CI:1.178~9.714,P=0.024)是术后切口愈合延迟的危险因素。结论肌少症可作为接受根治性结直肠癌切除的老年病人术后切口愈合延迟的重要预测指标。

关键词: 切口愈合延迟, 肌少症, 结直肠癌, 老年人, 影响因素

Abstract: Objective To investigate the risk factors for delayed wound healing(DWH) in aged patients with colorectal cancer. Methods The clinical data of 104 patients who underwent radical resection for colorectal cancer at Department of General Surgery, Jiangsu Shengze Hospital from June 2020 to April 2024 were collected. All patients were divided into DWH group (n=24) and good wound healing group (n=80). The preoperative general clinical data, intraoperative and postoperative clinical indexes were compared between the two groups. Multivariate logistic regression analysis was used to investigate the influencing factors of DWH. Results The proportion of sarcopenia, age, proportion of diabetes, intraoperative bleeding volume and incidence rate of complications showed significant differences between the two groups. Multivariate logistic regression analysis showed that sarcopenia(OR=3.559,95%CI:1.203－10.53,P=0.022)and intraoperative bleeding(OR=3.383,95%CI:1.178－9.714,P=0.024)were risk factors of DWH. Conclusions Sarcopenia diagnosed through CT measurement of skeletal muscle index can serve as a significant predictor for DWH in the elderly patients undergoing radical resection of colorectal cancer.

Key words: delayed wound healing, sarcopenia, colorectal cancer, aged, risk factor

中图分类号:

R656.9

袁雄, 华浩东. 肌少症对老年结直肠癌病人术后切口愈合的影响[J]. 实用老年医学, 2025, 39(8): 798-801.

YUAN Xiong, HUA Haodong. Effects of sarcopenia on postoperative wound healing in elderly patients with colorectal cancer[J]. Practical Geriatrics, 2025, 39(8): 798-801.

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