实用老年医学 ›› 2022, Vol. 36 ›› Issue (12): 1264-1268.doi: 10.3969/j.issn.1003-9198.2022.12.019

• 临床研究 • 上一篇    下一篇

基于老年综合评估的2型糖尿病病人衰弱影响因素分析

包海童, 谈萍, 俞沛文, 刘娟, 丁国宪, 佟蔷薇, 王晓东   

  1. 210029 江苏省南京市,江苏省人民医院(南京医科大学第一附属医院)老年内分泌2病区
  • 收稿日期:2021-10-21 出版日期:2022-12-20 发布日期:2022-11-30
  • 通讯作者: 佟蔷薇,Email: lizahaitong@163.com
  • 基金资助:
    江苏省卫生健康委员会科研课题(BJ17015)

Analysis of influencing factors of frailty based on geriatric comprehensive assessment in the elderly patients with type 2 diabetes mellitus

BAO Hai-tong, TAN Ping, YU Pei-wen, LIU Juan, DING Guo-xian, TONG Qiang-wei, WANG Xiao-dong   

  1. Department of Geriatric Endocrine, Jiangsu Province Hospital (the First Affiliated Hospital of Nanjing Medical University), Nanjing 210029, China
  • Received:2021-10-21 Online:2022-12-20 Published:2022-11-30

摘要: 目的 采用老年综合评估的方法对老年2型糖尿病病人进行衰弱的影响因素分析。 方法 采用便利抽样,选取江苏省人民医院2020年1月至2021年6月210例老年2型糖尿病病人作为研究对象,自制一般资料调查表了解病人的基本信息,采用生理衰弱评估量表(PFP)筛查病人的衰弱状况,采用微型营养评估量表(MNA)、MMSE、老年抑郁评估量表(GDS)、住院病人多维预后指数评分(MPI)、4 m步速、起立行走计时测试(TUG)、双重任务起立行走测试(TUGman)、双重任务起立行走认知测试(TUGcog)等分别评估病人的营养、认知、心理、预后及躯体功能状况,采用Logistic回归分析老年2型糖尿病病人衰弱发生的影响因素。 结果 衰弱组与非衰弱组性别、年龄、婚姻状况、居住状况、糖尿病病程、营养状态、认知状态、心理状态、全因死亡风险、跌倒风险、步速和握力、TUG、HbA1c、BMI差异均有统计学意义。Logistic回归分析结果显示,女性、糖尿病病程长、握力小、4 m步速慢为老年2型糖尿病病人衰弱发生的独立影响因素。 结论 对于老年2型糖尿病病人,衰弱评估需要多元化,采用老年综合评估的方法可以了解老年2型糖尿病病人衰弱发生的危险因素,及时采取针对性的干预,改善衰弱状况及预防不良结局的发生,提高病人的生存质量。

关键词: 老年人, 糖尿病, 衰弱, 老年综合评估

Abstract: Objective To analyze the influencing factors of frailty in the elderly patients with type 2 diabetes mellitus (T2DM) by comprehensive geriatric assessment. Methods A total of 210 patients with T2DM aged ≥ 65 years old who were hospitalized in the Department of Geriatric Endocrine of Jiangsu Province Hospital from January 2020 to June 2021 were enrolled and divided into frailty group and non-frailty group according to the results of Physical Frailty Phenotype(PFP). The status of nutrition, cognition, psychology, prognosis and physical function of the patients were measured by Mini Nutritional Assessment Scale (MNA), Mini-mental State Examination (MMSE), Geriatric Depression Scale (GDS), Multidimensional Prognostic Index (MPI) score for inpatients, 4 m walking speed, Timed Up and Go (TUG) test, TUG manual (TUGman), TUG cognitive (TUGcog), respectively. Binary Logistic regression analysis was used to analyze the influencing factors of frailty in the hospitalized elderly patients with T2DM. Results There were significant differences in gender, age, marital status, residential status, course of disease, nutritional status, cognitive status, psychological status, risk of death, risk of fall, walking speed, TUG, glycated hemoglobin, body mass index and grip strength between two groups(P<0.05). Binary Logistic regression analysis showed that female, long course of diabetes, low grip strength and low 4 m walking speed were the risk factors of frailty in the hospitalized elderly patients with T2DM. Conclusions The assessment of frailty in the elderly patients with T2DM needs to be diversified. The comprehensive geriatric assessment method for the elderly can be used to investigate the influencing factors of frailty in the elderly patients with T2DM and improve the quality of life.

Key words: aged, diabetes, frailty, comprehensive geriatric assessment

中图分类号: