183例老年过敏性紫癜住院病人临床特征分析

doi:10.3969/j.issn.1003-9198.2023.01.011

摘要/Abstract

摘要： 目的探讨老年过敏性紫癜(Henoch-Schonlein purpura, HSP) 的临床特征。方法对2002年3月至2021年6月于我院住院治疗的年龄≥60岁的HSP病人183例病历资料进行回顾性分析。结果 183例老年HSP病人平均(69.41±6.81)岁,男女比例为1∶1.316;秋冬季为其高发季节。临床类型以肾型紫癜(47.00%)和混合型紫癜(40.98%)为多见。在发病诱因方面,感染(占32.2%)为其发病的主要原因,主要为上呼吸道感染(72.9%)。病程中42.6%的病人发生了消化道损害,其中男性病人多于女性,差异有统计学意义(P<0.05)。此外,纤维蛋白降解产物(FDP)水平升高的比例在有/无胃肠道受累组间差异有统计学意义(P<0.05)。结论老年女性HSP病人多于男性;以秋冬季节发病为主,肾型紫癜和混合型紫癜为主要临床类型;老年HSP男性病人易发生消化道损害,监测血FDP值有助于辅助诊断有无消化道损害。

关键词: 过敏性紫癜, 临床特征, 老年人, 回顾性分析

Abstract: Objective To investigate the clinical characteristics of Henoch-Schonlein purpura (HSP) in the elderly. Methods A total of 183 elderly inpatients with HSP aged ≥60 years old in the First Affiliated Hospital of Anhui Medical University from March 2002 to June 2021 were retrospectively analyzed. Results Among 183 elderly inpatients with HSP, the average age was 69.41±6.81 years, and the ratio of male to female patients was 1∶1.316. The disease occurred mostly in autumn and winter. The main clinical types of elderly HSP patients were renal purpura (47.00%) and mixed purpura (40.98%). The main predisposing factor of HSP was infection (32.2%), and the main type of infection was upper respiratory tract infection (72.9%). Gastrointestinal damage occurred in 42.6% of the patients during the course of the disease. In addition, the increased fibrin degradation products (FDP) level was statistically different between the patients with gastrointestinal damage and those without gastrointestinal damage (P<0.05). Conclusions The incidence of HSP in the elderly patients is associated with the gender and season, and the main clinical types of HSP in the elderly were renal purpura and mixed purpura. The elderly patients with HSP are prone to develop gastrointestinal damage, and monitoring blood FDP level is helpful to determine the occurrence of gastrointestinal damage.

Key words: Henoch-Schonlein purpura, clinical manifestation, aged, retrospective analysis

中图分类号:

R 554.6

曹艳, 张安平. 183例老年过敏性紫癜住院病人临床特征分析[J]. 实用老年医学, 2023, 37(1): 43-46.

CAO Yan, ZHANG An-ping. Clinical characteristics of 183 elderly inpatients with Henoch-Schonlein purpura[J]. Practical Geriatrics, 2023, 37(1): 43-46.

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