老年2型糖尿病伴抑郁病人负性情绪与糖脂代谢指标关系探讨

doi:10.3969/j.issn.1003-9198.2021.06.013

摘要/Abstract

摘要： 目的探讨老年T2DM伴抑郁病人负性情绪与糖脂代谢指标的关系。方法选取医院2019年1月至2020年10月收治的84例老年T2DM伴抑郁病人(研究组)与79例老年T2DM病人(对照组)为研究对象,对比2组负性情绪及糖脂代谢指标水平,分析研究组病人负性情绪与糖脂代谢指标的相关性。结果研究组汉密尔顿抑郁量表(HAMD)评分高于对照组(P＜0.05),领悟社会支持量表(PSSS)评分低于对照组(P＜0.05);研究组FPG、HbA1c、胰岛素抵抗指数(HOMA-IR)、TG、TC水平均高于对照组(P＜0.05);研究组FPG、HbA1c、HOMA-IR、TG、TC水平均与HAMD评分呈正相关(P＜0.05),与PSSS评分呈负相关(P＜0.05)。结论老年T2DM伴抑郁病人负性情绪与糖脂代谢密切相关,负性情绪越严重,糖脂代谢越紊乱,建议临床加强心理情绪治疗。

关键词: 2型糖尿病, 抑郁, 负性情绪, 糖脂代谢

Abstract: Objective To explore the relationship between negative emotion and the indexes of glucose and lipid metabolism in the elderly patients with type 2 diabetes mellitus (T2DM) complicated with depression. Methods A total of 84 elderly patients with T2DM complicated with depression (study group) and 79 elderly T2DM patients (control group) admitted to the hospital from January 2019 to October 2020 were selected as the research objects. The negative emotion and the glucose and lipid metabolism of the two groups were compared. The correlation between negative emotions and the indicators of glucose and lipid metabolism in the study group was analyzed. Results The scores of the Anxiety Self-Rating Scale (SAS) and the Hamilton Depression Scale (HAMD) in the study group were higher than those in the control group (P<0.05), and the score of Perceived Social Support Scale (PSSS) in the study group was lower than that in the control group (P <0.05). The levels of fasting blood glucose (FPG), glycosylated hemoglobin (HbA1c), insulin resistance index (HOMA-IR), triglycerides (TG) and total cholesterol (TC) in the study group were higher than those in the control group (P＜0.05). The levels of FPG, HbA1c, HOMA-IR, TG and TC in the study group were positively correlated with HAMD score (P<0.05), and were negatively correlated with PSSS score (P<0.05 ). Conclusions Negative emotion is closely related to glucose and lipid metabolism in the elderly patients with T2DM and depression. The more serious the negative emotions, the more disordered the glucose and lipid metabolism. It is recommended to strengthen clinical health education and psycho-emotional treatment.

Key words: type 2 diabetes mellitus, depression, negative emotions, glycolipid metabolism

中图分类号:

R 587.2

陈涛, 顾滔. 老年2型糖尿病伴抑郁病人负性情绪与糖脂代谢指标关系探讨[J]. 实用老年医学, 2021, 35(6): 588-590.

CHEN Tao, GU Tao. Relationship between negative emotion and glucose and lipid metabolism in elderly patients with type 2 diabetes and depression[J]. Practical Geriatrics, 2021, 35(6): 588-590.

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