Abstract: Objective To explore the correlation between intestinal dynamics and quality of life in the patients with chronic obstructive pulmonary disease(COPD). Methods Forty-five patients with COPD at the First Affiliated Hospital with Nanjing Medical University were enrolled by cross-sectional survey, and 45 healthy subjects were recruited from the society. The intestinal motility of the two groups was detected by gastrointestinal motility instrument, and their physiological and psychological status was evaluated by 36-item short form health survey(SF-36) questionnaire. Results The amplitude of ascending colon, transverse colon and the amplitude and frequency of descending colon in COPD group were higher than those in healthy group(P<0.05 or P<0.01). The scores of physical functioning(PF), role physical(RP), role emotional(RE), vitality(VT) and social functioning(SF) in SF-36 of the healthy group were significantly higher than those of COPD group(P<0.01). Intestinal motility was negatively correlated with PF, RE, SF, RP and VT in the patients with COPD (all P<0.05). Conclusions The intestinal motility in the patients with COPD is higher than that in healthy people. The disorder of intestinal dynamics shows a negative impact on the quality of life in the patients with COPD.

Key words: chronic obstructive pulmonary disease, intestinal dynamics, quality of life