体型指数与年龄相关性黄斑变性之间的关系

doi:10.3969/j.issn.1003-9198.2026.04.009

Abstract

Abstract: Objective To explore the association between a body shape index (ABSI) and the risk of age-related macular degeneration (AMD). Methods Based on the cross-sectional data of the National Health and Nutrition Examination Survey (NHANES) from 2005 to 2008, a multivariable logistic regression model considering the complex sampling design of NHANES was used to analyze the association between ABSI and AMD. The restricted cubic spline (RCS) analysis was conducted to explore the dose-response relationship between ABSI and AMD. Results A total of 4 874 participants (365 cases of AMD) were included. After adjusting for all variables in the multivariable logistic regression model, ABSI remained significantly positively associated with AMD within the range of (7.95-8.28)×10^-2, the risk of AMD increased in the second quartile than that in the first quartile (OR=1.49,95%CI:1.01-2.20). RCS analysis showed that when ABSI was less than 8.28×10^-2, it is positively associated with AMD risk. Conclusions ABSI is independently associated with the risk of AMD within a certain range and may serve as a potential indicator for risk assessment and early screening, which suggesting that obesity management is significant for the prevention and control of AMD.

Key words: age-related macular degeneration, a body shape index, obesity

CLC Number:

R 774.5

WEI Meihui, SHI Wei, CHEN Xi, XU Xinrong, PAN Li. Association between a body shape index and age-related macular degeneration[J]. Practical Geriatrics, 2026, 40(4): 372-376.

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Association between a body shape index and age-related macular degeneration

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