睡眠结构紊乱对阿尔茨海默病的影响研究进展

doi:10.3969/j.issn.1003-9198.2026.03.018

Abstract

Abstract: AD is a common neurodegenerative disease, characterized by progressive cognitive decline and gradually worsening neuropsychiatric symptoms. Studies have found that sleep structure disorder is one of the important risk factors of Alzheimer’s disease, which is closely related to the pathological formation of β-amyloid and tau proteins in the brain as well as the structural and functional changes of related brain regions. Meanwhile, sleep structure disorder can worsen cognitive dysfunction and play an important role in the progression of AD. Therefore, sleep intervention has the potential to serve as a future strategy for the early prevention and treatment of AD.

Key words: Alzheimer’s disease, sleep architecture, cognitive function, β-amyloid, tau protein

CLC Number:

R 749.16

XU Zhicong, DONG Jingde. Research progress on the effects of sleep architecture disruption on Alzheimer’s disease[J]. Practical Geriatrics, 2026, 40(3): 315-319.

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Research progress on the effects of sleep architecture disruption on Alzheimer’s disease

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