Abstract: Objective To investigate the risk factors for delayed wound healing(DWH) in aged patients with colorectal cancer. Methods The clinical data of 104 patients who underwent radical resection for colorectal cancer at Department of General Surgery, Jiangsu Shengze Hospital from June 2020 to April 2024 were collected. All patients were divided into DWH group (n=24) and good wound healing group (n=80). The preoperative general clinical data, intraoperative and postoperative clinical indexes were compared between the two groups. Multivariate logistic regression analysis was used to investigate the influencing factors of DWH. Results The proportion of sarcopenia, age, proportion of diabetes, intraoperative bleeding volume and incidence rate of complications showed significant differences between the two groups. Multivariate logistic regression analysis showed that sarcopenia(OR=3.559,95%CI:1.203－10.53,P=0.022)and intraoperative bleeding(OR=3.383,95%CI:1.178－9.714,P=0.024)were risk factors of DWH. Conclusions Sarcopenia diagnosed through CT measurement of skeletal muscle index can serve as a significant predictor for DWH in the elderly patients undergoing radical resection of colorectal cancer.

Key words: delayed wound healing, sarcopenia, colorectal cancer, aged, risk factor