Abstract: Objective To investigate the characteristics and influencing factors of the medication adherence to phosphorus binding agent in the elderly patients undergoing maintenance hemodialysis(MHD) in the close-type medical association. Methods The elderly patients who were treated in three dialysis centers of close-type medical association in our hospital from June to December 2020 were enrolled. The patients were investigated by general information questionnaire, simplified medication compliance questionnaire and laboratory indicators, and the relevant influencing factors of medication adherence were analyzed. Results A total of 327 patients were surveyed and 312 patients completed, the effective recovery was 95.4%. Out of the patients, 252 cases(70.8%) had good adherence to phosphorus binding agent, and 60 patients(19.2%) had poor compliance. The blood phosphorus control rate in the good compliance group was significantly higher than that in the poor compliance group. Logistic regression analysis showed that dialysis age and primary diseases were the influencing factors of medication compliance(P<0.05). The medication compliance in the center was significantly higher than that in the two subcenters(P<0.05), but there was no significant difference between the two subcenters(P>0.05). Conclusions The adherence to phosphorus binding agent in the elderly MHD patients needs to be further improved. The dialysis age and the primary diseases in the elderly patients are the independent risk factors affecting the adherence to phosphorus binding agent.

Key words: phosphorus binding agent, maintenance hemodialysis, close-type medical association, medication adherence