绝经后女性肥胖相关指数与心血管疾病风险的关联分析

doi:10.3969/j.issn.1003-9198.2025.04.010

摘要/Abstract

摘要： 目的比较多种肥胖相关人体测量指数在预测心血管疾病(cardiovascular disease, CVD)风险方面的效能,并确定最佳指标的最佳阈值。方法本项横断面研究调查了1 702例居住在中国南京城市地区年龄＞60岁的绝经后女性。记录8项肥胖相关人体测量指数,包括体质量指数、腰围、腰臀比、腰高比、腹部容积指数、身体肥胖指数、体圆度指数和体型指数。采用多因素logistic回归分析评估10年CVD风险与所有指标之间的相关性。采用ROC曲线和AUC评估所有指标对CVD风险的预测能力。结果在这些绝经后女性中,691例(40.6%)被评估为CVD中风险,406例(23.9%)被评估为CVD高风险。有中高CVD风险的人具有更高水平的肥胖相关人体测量指数。多因素logistic回归分析结果显示,除体型指数外,其余所有肥胖相关人体测量指数均与CVD风险相关。ROC曲线分析显示,身体圆度指数和腰高比对CVD风险有更优的筛查性能,最佳阈值分别为3.85和0.52。结论身体圆度指数和腰高比是评估绝经后女性CVD风险的最佳人体测量指标。

Abstract: Objective To compare the predicting value of the obesity-related indices for the risk of cardiovascular disease(CVD) in the postmenopausal women, and to determine the optimal cut off point for the best indicators. Methods This cross-sectional study surveyed 1 702 postmenopausal women aged over 60 years old living in the urban area of Nanjing, China. Eight obesity-related anthropometric indices were studied, including body mass index, waist circumference, waist-to-hip ratio, waist-to-height ratio, abdominal volume index, body obesity index, body roundness index and body shape index. Logistic regression analysis was used to evaluate the correlation between 10-year CVD risk and all indicators. The receiver operating characteristic(ROC) curve and the area under the curve(AUC)were used to evaluate the predictive value of all indicators for CVD risk. Results Among these postmenopausal women, 691(40.6%) cases presented with medium risk of CVD, and 406(23.9%) with high risk of CVD. People with moderate to high CVD risk had higher levels of body measurement indices. Logistic regression analysis showed that all anthropometric indices were statistically correlated with CVD risk except for body shape index. ROC analysis showed that body roundness index and waist-to-height ratio had higher predicting value for CVD risk, with optimal cut-off value as 3.85 and 0.52, respectively. Conclusions Body roundness index and waist-to-height ratio are the best anthropometric indicators for assessing CVD risk in postmenopausal women.

Key words: cardiovascular disease risk, obesity-related indices, waist-to-height ratio, body roundness index, postmenopausal women

中图分类号:

R 54

郑卉, 王惠, 尹冬华, 尹红丽, 孙楚乔, 程阳, 王颖. 绝经后女性肥胖相关指数与心血管疾病风险的关联分析[J]. 实用老年医学, 2025, 39(4): 372-376.

ZHENG Hui, WANG Hui, YIN Donghua, YIN Hongli, SUN Chuqiao,CHENG Yang, WANG Ying. Analysis of the correlation between obesity-related indices and risk of cardiovascular disease in postmenopausal women[J]. Practical Geriatrics, 2025, 39(4): 372-376.

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