实用老年医学 ›› 2021, Vol. 35 ›› Issue (11): 1170-1173.doi: 10.3969/j.issn.1003-9198.2021.11.016

• 临床研究 • 上一篇    下一篇

老年2型糖尿病住院病人共病情况分析

纪倩云, 李曼, 崔雯霞, 高蕾, 潘丰慧, 张铭瑞, 胡云   

  1. 210008 江苏省南京市,南京医科大学鼓楼临床医学院老年科
  • 收稿日期:2020-12-25 发布日期:2021-11-23
  • 通讯作者: 胡云,Email:huyundr@sina.com
  • 基金资助:
    江苏省卫计委科研基金资助项目(BJ17003)

Analysis of comorbidities in elderly inpatients with type 2 diabetes mellitus

JI Qian-yun, LI Man, CUI Wen-xia, GAO Lei, PAN Feng-hui, ZHANG Ming-rui, HU Yun   

  1. Department of Geriatrics, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing 210008, China
  • Received:2020-12-25 Published:2021-11-23

摘要: 目的 了解老年T2DM住院病人的共病情况。 方法 采用回顾性研究方法,收集我科住院的427例老年T2DM病人的临床资料,计算Charlson共病指数(CCI),并根据CCI得分分为低共病组(≤2分)和高共病组(>2分)。分析2组病人的一般情况、伴发疾病、血糖控制和多重用药情况。 结果 427例老年T2DM病人中,高共病患病率(CCI>2分)为65.34%(279/427)。高共病组的年龄和糖尿病病程显著大于低共病组,差异有统计学意义(P<0.05)。高共病组中有88.53%伴发高血压、81.00%伴发高血脂、63.44%伴发外周动脉血管疾病、60.93%伴发脑血管病、40.50%伴发缺血性心脏病,低共病组中有77.70%伴发高血脂、62.84%伴发外周动脉血管疾病、53.38%伴发高血压。高共病组伴多重用药的比例(62.37%)显著高于低共病组(47.30%),差异有统计学意义(P<0.01)。低共病组和高共病组血糖控制及胰岛功能比较,差异没有统计学意义(P>0.05)。 结论 老年T2DM高共病病人较低共病病人年龄大、病程长、多重用药比例高,更容易伴发高血压和心脑血管疾病。

关键词: 2型糖尿病, 老年人, 共病, 多重用药

Abstract: Objective To investigate the comorbidities in the elderly patients with type 2 diabetes mellitus (T2DM). Methods A retrospective study was conducted to collect clinical data of 427 hospitalized elderly patients with T2DM. The Charlson comorbidity index (CCI) was calculated. CCI≤2 was defined as low comorbidity group, and CCI > 2 was defined as high comorbidity group. The general condition, comorbidites, blood glucose control and multiple drug use were analyzed in different comorbidity group. Results Among 427 elderly patients with T2DM, the high comorbidities prevalence was 65.34%. The age and course of diabetes of the high comorbidity group were significantly higher than those of the low comorbidity group (P<0.05).In the high comorbidity group, 88.53% were complicated with hypertension, 81.00% with hyperlipidemia, 63.44% with peripheral artery disease, 60.93% with cerebrovascular disease, and 40.50% with ischemic heart disease. In the low comorbidity group, 77.70% were complicated with hyperlipidemia, 62.84% with peripheral artery disease, and 53.38% with hypertension. The proportion of polypharmacy in high comorbidity group (62.37%) was significantly higher than that of low comorbidity group (47.30%) (P<0.01). There were no significant differences in blood glucose control and islet function between low comorbidity group and high comorbidity group (P>0.05). Conclusions Compared with the low comorbidity group, the patients in the high comorbidity group show older age, longer course of disease, higher proportion of taking multiple drugs, and are more likely to be complicated with diseases such as hypertension, cardiovascular and cerebrovascular diseases.

Key words: type 2 diabetes mellitus, aged, comorbidity, polypharmacy

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