实用老年医学

实用老年医学 ›› 2021, Vol. 35 ›› Issue (5): 455-458.doi: 10.3969/j.issn.1003-9198.2021.05.006

• 临床研究 • 上一篇    下一篇

老年终末期肾病腹膜透析病人身体功能与抑郁症状关系的横断面研究

章海芬, 黄佳颖, 顾爱萍, 赖岚书慧, 陶幸娟   

  1. 200127 上海市,上海交通大学医学院附属仁济医院肾脏科(章海芬,黄佳颖,顾爱萍,赖岚书慧);
    200025 上海市,上海交通大学护理学院(陶幸娟)
  • 收稿日期:2020-06-02 出版日期:2021-05-20 发布日期:2021-05-25
  • 通讯作者: 陶幸娟,Email: tao.xingjuan@shsmu.edu.cn
  • 基金资助:
    国家自然科学基金青年科学基金项目(71704105)

Association between physical performance and depressive symptoms in elderly patients with end-stage renal disease undergoing peritoneal dialysis: a cross-sectional study

ZHANG Hai-fen, HUANG Jia-ying, GU Ai-ping, LAI-LAN Shu-hui, TAO Xing-juan   

  1. ZHANG Hai-fen, HUANG Jia-ying, GU Ai-ping, LAI-LAN Shu-hui. Department of Nephrology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China;
    TAO Xing-juan. School of Nursing, Shanghai Jiao Tong University, Shanghai 200025, China
  • Received:2020-06-02 Online:2021-05-20 Published:2021-05-25

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摘要： 目的 研究老年终末期肾病腹膜透析(peritoneal dialysis, PD)病人4项身体功能评估结果与抑郁症状水平的相关关系,并筛选与病人发生抑郁症状关联的身体功能指标。方法 采用简易版老年抑郁量表(GDS-15)对年龄≥60岁的PD病人进行抑郁症状评估。以5次坐立测试(5-repetition sit-to-stand, 5-STS)、握力(handgrip strength, HGS)、日常步行速度(gait speed, GS)以及计时起立行走(timed up and go, TUG)评估病人身体功能。采用多元Logistic回归分析筛选影响老年PD病人抑郁症状的身体功能指标。结果 研究共纳入115例老年PD病人,72.2%病人GDS-15>5分,存在抑郁症状。抑郁组病人4项身体功能评分均明显低于非抑郁组(P<0.05),退休金<3000元/月的比例高于非抑郁组(P<0.05)。5-STS(r=0.264)、GS(r=-0.242)、TUG(r=0.399)与GDS-15评分相关(均P<0.05)。多因素Logistic回归分析显示,TUG 表现受限是老年病人发生抑郁症状的危险因素(OR=5.293,95%CI:1.013~27.651)。结论 老年终末期肾病PD病人抑郁症状发生率高,TUG表现受限是病人发生抑郁症状的危险因素。

关键词: 终末期肾病, 腹膜透析, 老年人, 身体功能, 抑郁

Abstract: Objective To explore the association between performance-based physical function and depressive symptoms in the elderly patients with end-stage renal disease undergoing peritoneal dialysis(PD). Methods Physical function was assessed by handgrip strength (HGS), timed up and go (TUG) test, 5-repetition sit-to-stand test (5-STS) and comfortable gait speed (GS). Depressive symptoms were measured by using the Geriatric Depression Scale (GDS-15). Multiple Logistic regression analysis was performed to investigate the factors that influenced the depressive symptoms. Results A total of 115 PD patients with a mean age of 69.7 years old were included. 72.2% of the patients showed a GDS-15 score more than 5. The patients with depressive symptoms presented with poorer physical performance, and had a higher percentage reporting in income level less than 3000 RMB/month(P<0.05). The levels of 5-STS(r=0.264), GS(r=-0.242), TUG(r=0.399)performance were significantly associated with GDS-15 score. TUG impairment was a risk factor of depressive symptoms(OR=5.293,95%CI:1.013-27.651). Conclusions There is a high prevalence of depressive symptoms in the elderly patients undegoing PD, and TUG performance is associated with the depressive symptoms.

Key words: end-stage renal disease, peritoneal dialysis, aged, physical function, depressive symptoms

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